1-benzyl-N-{[1-(2-hydroxyethyl)-1H-1,2,3-triazol-4-yl]methyl}-1H-1,2,3-triazole-4-carboxamide

Base Information

Chemical Name:1-benzyl-N-{[1-(2-hydroxyethyl)-1H-1,2,3-triazol-4-yl]methyl}-1H-1,2,3-triazole-4-carboxamide
CAS No.:1267623-14-2
Molecular Formula:C₁₅H₁₇N₇O₂
Molecular Weight:327.346
Hs Code.:

Synonyms:1-benzyl-N-{[1-(2-hydroxyethyl)-1H-1,2,3-triazol-4-yl]methyl}-1H-1,2,3-triazole-4-carboxamide

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Chemical Property of 1-benzyl-N-{[1-(2-hydroxyethyl)-1H-1,2,3-triazol-4-yl]methyl}-1H-1,2,3-triazole-4-carboxamide

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Technology Process of 1-benzyl-N-{[1-(2-hydroxyethyl)-1H-1,2,3-triazol-4-yl]methyl}-1H-1,2,3-triazole-4-carboxamide

There total 3 articles about 1-benzyl-N-{[1-(2-hydroxyethyl)-1H-1,2,3-triazol-4-yl]methyl}-1H-1,2,3-triazole-4-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 1517-05-1
2-azidoethanol

: 1245932-54-0
C₁₃H₁₂N₄O

: 1267623-14-2
1-benzyl-N-{[1-(2-hydroxyethyl)-1H-1,2,3-triazol-4-yl]methyl}-1H-1,2,3-triazole-4-carboxamide

Guidance literature:: With copper(l) iodide; In dichloromethane; at 20 ℃; chemoselective reaction;
DOI:10.1016/j.tetlet.2010.11.141

Reference yield:

: 622-79-7
benzyl azide

: 1267623-14-2
1-benzyl-N-{[1-(2-hydroxyethyl)-1H-1,2,3-triazol-4-yl]methyl}-1H-1,2,3-triazole-4-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: 18 h / 20 °C

2: copper(l) iodide / dichloromethane / 20 °C

With copper(l) iodide; In dichloromethane; 1: Huisgen's reaction / 2: copper catalyzed Huisgen's reaction;
DOI:10.1016/j.tetlet.2010.11.141

Reference yield:

: N-(prop-2-yn-1-yl)prop-2-ynamide

: 1267623-14-2
1-benzyl-N-{[1-(2-hydroxyethyl)-1H-1,2,3-triazol-4-yl]methyl}-1H-1,2,3-triazole-4-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: 18 h / 20 °C

2: copper(l) iodide / dichloromethane / 20 °C

With copper(l) iodide; In dichloromethane; 1: Huisgen's reaction / 2: copper catalyzed Huisgen's reaction;
DOI:10.1016/j.tetlet.2010.11.141