(R)-3-(3-cyclopentyloxy-4-methoxyphenyl)pentanedioic acid monobenzyl ester

Base Information

Chemical Name:(R)-3-(3-cyclopentyloxy-4-methoxyphenyl)pentanedioic acid monobenzyl ester
CAS No.:1427298-75-6
Molecular Formula:C₂₄H₂₈O₆
Molecular Weight:412.483
Hs Code.:

Synonyms:(R)-3-(3-cyclopentyloxy-4-methoxyphenyl)pentanedioic acid monobenzyl ester

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Chemical Property of (R)-3-(3-cyclopentyloxy-4-methoxyphenyl)pentanedioic acid monobenzyl ester

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Technology Process of (R)-3-(3-cyclopentyloxy-4-methoxyphenyl)pentanedioic acid monobenzyl ester

There total 6 articles about (R)-3-(3-cyclopentyloxy-4-methoxyphenyl)pentanedioic acid monobenzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1427298-76-7
C₂₄H₂₈O₆*C₈H₁₁N

: 1427298-75-6
(R)-3-(3-cyclopentyloxy-4-methoxyphenyl)pentanedioic acid monobenzyl ester

Guidance literature:: With hydrogenchloride; In water; toluene; Inert atmosphere;
DOI:10.1016/j.tetasy.2013.01.009

Reference yield:

: 1427298-74-5
4-(3-cyclopentyloxy-4-methoxyphenyl)dihydropyran-2,6-dione

: 100-51-6,185532-71-2
benzyl alcohol

: 1427298-78-9
(S)-3-(3-cyclopentyloxy-4-methoxyphenyl)pentanedioic acid monobenzyl ester

: 1427298-75-6
(R)-3-(3-cyclopentyloxy-4-methoxyphenyl)pentanedioic acid monobenzyl ester

Guidance literature:: With quinindine; In toluene; at -30 ℃; for 168h; Temperature; Reagent/catalyst; Overall yield = 93 %; enantioselective reaction; Inert atmosphere;
DOI:10.1016/j.tetasy.2013.01.009

Reference yield:

: 172970-89-7
3-(3-cyclopentyloxy-4-methoxyphenyl)pentanedioic acid

: 1427298-75-6
(R)-3-(3-cyclopentyloxy-4-methoxyphenyl)pentanedioic acid monobenzyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: acetic anhydride / 0.5 h / 110 °C / Inert atmosphere

2: quinindine / toluene / 168 h / -30 °C / Inert atmosphere

With quinindine; acetic anhydride; In toluene;
DOI:10.1016/j.tetasy.2013.01.009