methyl (E)-3-[2,2-dimethoxyethyl(4-methylbenzenesulfonyl)amino]acrylate

Base Information

• Chemical Name: methyl (E)-3-[2,2-dimethoxyethyl(4-methylbenzenesulfonyl)amino]acrylate
• CAS No.: 950777-49-8
• Molecular Formula: C₁₅H₂₁NO₆S
• Molecular Weight: 343.401

Synonyms:methyl (E)-3-[2,2-dimethoxyethyl(4-methylbenzenesulfonyl)amino]acrylate

Chemical Property of methyl (E)-3-[2,2-dimethoxyethyl(4-methylbenzenesulfonyl)amino]acrylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl (E)-3-[2,2-dimethoxyethyl(4-methylbenzenesulfonyl)amino]acrylate

There total 2 articles about methyl (E)-3-[2,2-dimethoxyethyl(4-methylbenzenesulfonyl)amino]acrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

N-(2,2-dimethoxyethyl)-p-toluenesulfonamide (58754-95-3) + propynoic acid methyl ester (922-67-8) → methyl (E)-3-[2,2-dimethoxyethyl(4-methylbenzenesulfonyl)amino]acrylate (950777-49-8) + methyl (Z)-3-[2,2-dimethoxyethyl(4-methylbenzenesulfonyl)amino]acrylate

Guidance literature:

With 4-methyl-morpholine; In acetonitrile; at 0 ℃; for 2h;

DOI:10.1021/ol0711725

Reference yield:

N-(2,2-dimethoxyethyl)-p-toluenesulfonamide (58754-95-3) + propynoic acid methyl ester (922-67-8) → methyl (E)-3-[2,2-dimethoxyethyl(4-methylbenzenesulfonyl)amino]acrylate (950777-49-8)

Guidance literature:

With 4-methyl-morpholine; In acetonitrile; at 0 ℃; for 2h; diastereoselective reaction;

DOI:10.1002/chem.201003265

Reference yield: 99.0%

methyl (E)-3-[2,2-dimethoxyethyl(4-methylbenzenesulfonyl)amino]acrylate (950777-49-8) → N-(2,2-dimethoxyethyl)-N-((E)-3-hydroxyprop-1-enyl)-4-methylbenzenesulfonamide (950777-55-6)

Guidance literature:

With diisobutylaluminium hydride; In hexane; dichloromethane; at -78 ℃; for 1h;

DOI:10.1021/ol0711725

upstream raw materials:

N-(2,2-dimethoxyethyl)-p-toluenesulfonamide

propynoic acid methyl ester

Downstream raw materials:

N-(2,2-dimethoxyethyl)-N-((E)-3-hydroxyprop-1-enyl)-4-methylbenzenesulfonamide

N-(2,2-dimethoxyethyl)-N-{(E)-3-[(prop-2-ynyl)oxy]prop-1-enyl}-4-methylbenzenesulfonamide

N-(2,2-dimethoxyethyl)-N-{(E)-3-[(3-trimethylsilylprop-2-ynyl)oxy]prop-1-enyl}-4-methylbenzenesulfonamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 950777-49-8 methyl (E)-3-[2,2-dimethoxyethyl(4-methylbenzenesulfonyl)amino]acrylate

Send

Send

Metric Ton KG G Pound L ML

Send

Send