tert-butyl(((2R,3S)-3-((tert-butyldiphenylsilyl)oxy)-2,3-dihydrofuran-2-yl)methoxy)diphenylsilane

Base Information

• Chemical Name: tert-butyl(((2R,3S)-3-((tert-butyldiphenylsilyl)oxy)-2,3-dihydrofuran-2-yl)methoxy)diphenylsilane
• CAS No.: 105930-84-5
• Molecular Formula: C₃₇H₄₄O₃Si₂
• Molecular Weight: 592.926

Synonyms:tert-butyl(((2R,3S)-3-((tert-butyldiphenylsilyl)oxy)-2,3-dihydrofuran-2-yl)methoxy)diphenylsilane

Chemical Property of tert-butyl(((2R,3S)-3-((tert-butyldiphenylsilyl)oxy)-2,3-dihydrofuran-2-yl)methoxy)diphenylsilane

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyl(((2R,3S)-3-((tert-butyldiphenylsilyl)oxy)-2,3-dihydrofuran-2-yl)methoxy)diphenylsilane

There total 9 articles about tert-butyl(((2R,3S)-3-((tert-butyldiphenylsilyl)oxy)-2,3-dihydrofuran-2-yl)methoxy)diphenylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

3',5'-bis-O-(tert-butyldiphenylsilyl)-thymidine (118068-35-2) → tert-butyl(((2R,3S)-3-((tert-butyldiphenylsilyl)oxy)-2,3-dihydrofuran-2-yl)methoxy)diphenylsilane (105930-84-5)

Guidance literature:

With 2,6-dimethylpyridine; N,O-bis-(trimethylsilyl)-acetamide; bis(diphenylthiophosphinoyl)amine; In n-heptane; toluene; at 100 ℃; for 3h; Inert atmosphere;

DOI:10.1021/acs.joc.1c00555

Reference yield: 89.0%

3-(tert-butyl-diphenyl-silanyloxy)-2-(tert-butyl-diphenyl-silanyloxymethyl)-4-phenylselanyl-tetrahydro-furan → tert-butyl(((2R,3S)-3-((tert-butyldiphenylsilyl)oxy)-2,3-dihydrofuran-2-yl)methoxy)diphenylsilane (105930-84-5)

Guidance literature:

3-(tert-butyl-diphenyl-silanyloxy)-2-(tert-butyl-diphenyl-silanyloxymethyl)-4-phenylselanyl-tetrahydro-furan; With titanium(IV) isopropylate; tert.-butylhydroperoxide; N-ethyl-N,N-diisopropylamine; In 1,2-dichloro-ethane; toluene;

In 1,2-dichloro-ethane; toluene; for 3h; Heating;

DOI:10.1016/S0008-6215(01)00256-7

Reference yield:

tert-butyl(((2R,3S)-3-((tert-butyldiphenylsilyl)oxy)-5-methoxytetrahydrofuran-2-yl)methoxy)diphenylsilane (148903-86-0) → tert-butyl(((2R,3S)-3-((tert-butyldiphenylsilyl)oxy)-2,3-dihydrofuran-2-yl)methoxy)diphenylsilane (105930-84-5)

Guidance literature:

Multi-step reaction with 2 steps

1: AcOH / tetrahydrofuran; H₂O / 6 h / 65 °C

2: dehydration

With acetic acid; In tetrahydrofuran; water;

DOI:10.1021/ja00235a050

upstream raw materials:

3',5'-bis-O-(tert-butyldiphenylsilyl)-thymidine

tert-butylchlorodiphenylsilane

thymidine

2-deoxy-3,5-di-O-(tert-butyldiphenylsilyl)-D-ribonolactone

Downstream raw materials:

(4aS,6R,7S,7aS)-3-Benzyloxy-7-(tert-butyl-diphenyl-silanyloxy)-6-(tert-butyl-diphenyl-silanyloxymethyl)-4a,6,7,7a-tetrahydro-furo[3,2-e][1,3,4]oxadiazine-1-carboxylic acid benzyl ester

3-[(2R,5R)-4-(tert-Butyl-diphenyl-silanyloxy)-5-(tert-butyl-diphenyl-silanyloxymethyl)-2,5-dihydro-furan-2-yl]-5-chloro-pyrazine-2,6-diamine

((2R,3S)-3-(tert-butyldiphenylsilyloxy)-2,3-dihydrofuran-2-yl)methanol

C₂₂H₂₆N₂O₈

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 105930-84-5 tert-butyl(((2R,3S)-3-((tert-butyldiphenylsilyl)oxy)-2,3-dihydrofuran-2-yl)methoxy)diphenylsilane

Send

Send

Metric Ton KG G Pound L ML

Send

Send