methyl cis-1-benzoyl-1,2,3,4-tetrahydro-2-indol-3-ylpyridine-4-carboxylate

Base Information

Chemical Name:methyl cis-1-benzoyl-1,2,3,4-tetrahydro-2-indol-3-ylpyridine-4-carboxylate
CAS No.:107183-32-4
Molecular Formula:C₂₂H₂₀N₂O₃
Molecular Weight:360.412
Hs Code.:

Synonyms:methyl cis-1-benzoyl-1,2,3,4-tetrahydro-2-indol-3-ylpyridine-4-carboxylate

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Chemical Property of methyl cis-1-benzoyl-1,2,3,4-tetrahydro-2-indol-3-ylpyridine-4-carboxylate

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Technology Process of methyl cis-1-benzoyl-1,2,3,4-tetrahydro-2-indol-3-ylpyridine-4-carboxylate

There total 4 articles about methyl cis-1-benzoyl-1,2,3,4-tetrahydro-2-indol-3-ylpyridine-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 78061-46-8
1-Benzoyl-2-(1H-indol-3-yl)-1,2-dihydro-pyridine-4-carboxylic acid methyl ester

: 107183-32-4
methyl cis-1-benzoyl-1,2,3,4-tetrahydro-2-indol-3-ylpyridine-4-carboxylate

: 107183-31-3
methyl 1-benzoyl-1,2,3,6-tetrahydro-2-indol-3-ylpyridine-4-carboxylate

Guidance literature:: With hydrogen; palladium carbon; In tetrahydrofuran; for 3h; Ambient temperature;

Reference yield:

: 120-72-9
indole

: 107183-32-4
methyl cis-1-benzoyl-1,2,3,4-tetrahydro-2-indol-3-ylpyridine-4-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 32 percent / CH₂Cl₂ / 2 h / 0 °C

2: 15 percent / H₂ / 10percent palladium carbon / tetrahydrofuran / 3 h / Ambient temperature

With hydrogen; palladium carbon; In tetrahydrofuran; dichloromethane;

Reference yield:

: 2459-09-8
4-pyridinecarboxylic acid, methyl ester

: 107183-32-4
methyl cis-1-benzoyl-1,2,3,4-tetrahydro-2-indol-3-ylpyridine-4-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 32 percent / CH₂Cl₂ / 2 h / 0 °C

2: 15 percent / H₂ / 10percent palladium carbon / tetrahydrofuran / 3 h / Ambient temperature

With hydrogen; palladium carbon; In tetrahydrofuran; dichloromethane;