N-(2-chloro-5-(4-(4-methoxy-1-piperidinyl)-6-quinolinyl)-3-pyridinyl)-4-methoxybenzenesulfonamide

Base Information

Chemical Name:N-(2-chloro-5-(4-(4-methoxy-1-piperidinyl)-6-quinolinyl)-3-pyridinyl)-4-methoxybenzenesulfonamide
CAS No.:1201842-73-0
Molecular Formula:C₂₇H₂₇ClN₄O₄S
Molecular Weight:539.055
Hs Code.:

Synonyms:N-(2-chloro-5-(4-(4-methoxy-1-piperidinyl)-6-quinolinyl)-3-pyridinyl)-4-methoxybenzenesulfonamide

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Chemical Property of N-(2-chloro-5-(4-(4-methoxy-1-piperidinyl)-6-quinolinyl)-3-pyridinyl)-4-methoxybenzenesulfonamide

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Technology Process of N-(2-chloro-5-(4-(4-methoxy-1-piperidinyl)-6-quinolinyl)-3-pyridinyl)-4-methoxybenzenesulfonamide

There total 2 articles about N-(2-chloro-5-(4-(4-methoxy-1-piperidinyl)-6-quinolinyl)-3-pyridinyl)-4-methoxybenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 474707-27-2
1-(6-bromo-4-quinolyl)-4-piperidyl methyl ether

: 1112983-32-0
N-(2-chloro-5-(3,3,4,4-tetramethylborolan-1-yl)pyridin-3-yl)-4-methoxybenzenesulfonamide

: 1201842-73-0
N-(2-chloro-5-(4-(4-methoxy-1-piperidinyl)-6-quinolinyl)-3-pyridinyl)-4-methoxybenzenesulfonamide

Guidance literature:: With sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In ethanol; Inert atmosphere; Reflux;

Reference yield:

: 4045-24-3
4-methoxypiperidine

: 65340-70-7
6-bromo-4-chloroquinoline

: 1201842-73-0
N-(2-chloro-5-(4-(4-methoxy-1-piperidinyl)-6-quinolinyl)-3-pyridinyl)-4-methoxybenzenesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: ethanol; water / 3 h / 135 °C / microwave irradiation

2: sodium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / ethanol / Inert atmosphere; Reflux

With sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In ethanol; water;