4-benzylthiomethyl-5-hydroxy-exo-10-oxatricyclo<5.2.1.0^2,6>deca-4,8-dien-3-one

Base Information

• Chemical Name: 4-benzylthiomethyl-5-hydroxy-exo-10-oxatricyclo<5.2.1.0^2,6>deca-4,8-dien-3-one
• CAS No.: 127588-19-6
• Molecular Formula: C₁₇H₁₆O₃S
• Molecular Weight: 300.378
• Mol file: 127588-19-6.mol

Synonyms:4-benzylthiomethyl-5-hydroxy-exo-10-oxatricyclo<5.2.1.0^2,6>deca-4,8-dien-3-one

Chemical Property of 4-benzylthiomethyl-5-hydroxy-exo-10-oxatricyclo<5.2.1.0^2,6>deca-4,8-dien-3-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-benzylthiomethyl-5-hydroxy-exo-10-oxatricyclo<5.2.1.0^2,6>deca-4,8-dien-3-one

There total 1 articles about 4-benzylthiomethyl-5-hydroxy-exo-10-oxatricyclo<5.2.1.0^2,6>deca-4,8-dien-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

maleic anhydride (930-60-9) → 4-benzylthiomethyl-5-hydroxy-exo-10-oxatricyclo<5.2.1.02,6>deca-4,8-dien-3-one (127588-19-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 85 percent / 336 h

2: triethylamine / ethanol; H₂O / 0.5 h / Heating

With triethylamine; In ethanol; water;

DOI:10.1016/S0040-4020(01)89179-1

Reference yield: 25.0%

triethyloxonium fluoroborate (368-39-8) + 4-benzylthiomethyl-5-hydroxy-exo-10-oxatricyclo<5.2.1.02,6>deca-4,8-dien-3-one (127588-19-6) → benzyl(ethyl)sulfane (6263-62-3) + 4-benzylthiomethyl-5-ethoxy-exo-10-oxatricyclo<5.2.1.02,6>deca-4,8-dien-3-one (112698-58-5)

Guidance literature:

With triethylamine; In dichloromethane; for 3h; Ambient temperature;

DOI:10.1016/S0040-4020(01)89179-1

Reference yield:

4-benzylthiomethyl-5-hydroxy-exo-10-oxatricyclo<5.2.1.02,6>deca-4,8-dien-3-one (127588-19-6) → 4-benzylthiomethyl-exo-10-oxatricyclo<5.2.1.02,6>deca-4,8-dien-3-one (127588-00-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 45 percent / 1.) triethylamine / CH₂Cl₂ / 3 h / Ambient temperature

2: 1.) DIBAL; 2.) 3percent HCl / 1.) benzene, hexane, 3 days; 2.) water, dichloromethane, 1 h

With hydrogenchloride; diisobutylaluminium hydride; triethylamine; In dichloromethane;

DOI:10.1016/S0040-4020(01)89179-1

upstream raw materials:

maleic anhydride

Downstream raw materials:

benzyl(ethyl)sulfane

4-benzylthiomethyl-5-ethoxy-exo-10-oxatricyclo<5.2.1.0^2,6>deca-4,8-dien-3-one

4-benzylthiomethyl-exo-10-oxatricyclo<5.2.1.0^2,6>deca-4,8-dien-3-one