2-(p-aminophenoxy)methyl-3-chloro-7-methyl-4-m-toluidinoquinoline dihydrochloride

Base Information

Chemical Name:2-(p-aminophenoxy)methyl-3-chloro-7-methyl-4-m-toluidinoquinoline dihydrochloride
CAS No.:84489-95-2
Molecular Formula:C₂₄H₂₂ClN₃O*2ClH
Molecular Weight:476.833
Hs Code.:

Synonyms:2-(p-aminophenoxy)methyl-3-chloro-7-methyl-4-m-toluidinoquinoline dihydrochloride

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Chemical Property of 2-(p-aminophenoxy)methyl-3-chloro-7-methyl-4-m-toluidinoquinoline dihydrochloride

Chemical Property:

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Technology Process of 2-(p-aminophenoxy)methyl-3-chloro-7-methyl-4-m-toluidinoquinoline dihydrochloride

There total 3 articles about 2-(p-aminophenoxy)methyl-3-chloro-7-methyl-4-m-toluidinoquinoline dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 84489-93-0
[3-Chloro-7-methyl-2-(4-nitro-phenoxymethyl)-quinolin-4-yl]-m-tolyl-amine

: 84489-95-2
2-(p-aminophenoxy)methyl-3-chloro-7-methyl-4-m-toluidinoquinoline dihydrochloride

Guidance literature:: With hydrogen; nickel; In ethanol; for 0.666667h; under 2574.3 Torr;

Reference yield:

: 100-02-7,78813-13-5,89830-32-0
4-nitro-phenol

: 84489-95-2
2-(p-aminophenoxy)methyl-3-chloro-7-methyl-4-m-toluidinoquinoline dihydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: 65 percent / K₂CO₃ / ethanol / 8 h / Heating

2: 90 percent / H₂ / Raney Ni / ethanol / 0.67 h / 2574.3 Torr

With hydrogen; potassium carbonate; nickel; In ethanol;

Reference yield:

: 84489-77-0
(3-chloro-2-chloromethyl-7-methyl-[4]quinolyl)-m-tolyl-amine

: 84489-95-2
2-(p-aminophenoxy)methyl-3-chloro-7-methyl-4-m-toluidinoquinoline dihydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: 65 percent / K₂CO₃ / ethanol / 8 h / Heating

2: 90 percent / H₂ / Raney Ni / ethanol / 0.67 h / 2574.3 Torr

With hydrogen; potassium carbonate; nickel; In ethanol;