4-(6-Acetyl-1,3,7-trimethyl-2,4-dioxo-1,2,3,4,5,8-hexahydropyrido[2,3-D]pyrimidin-5-YL)benzoic acid

Base Information

Chemical Name:4-(6-Acetyl-1,3,7-trimethyl-2,4-dioxo-1,2,3,4,5,8-hexahydropyrido[2,3-D]pyrimidin-5-YL)benzoic acid
CAS No.:848029-08-3
Molecular Formula:C₁₉H₁₉N₃O₅
Molecular Weight:369.377
Hs Code.:
DSSTox Substance ID:DTXSID10479389
Nikkaji Number:J2.139.186G
Mol file:848029-08-3.mol

Synonyms:848029-08-3;4-(6-ACETYL-1,3,7-TRIMETHYL-2,4-DIOXO-1,2,3,4,5,8-HEXAHYDROPYRIDO[2,3-D]PYRIMIDIN-5-YL)BENZOIC ACID;BENZOIC ACID,4-(6-ACETYL-1,2,3,4,5,8-HEXAHYDRO-1,3,7-TRIMETHYL-2,4-DIOXOPYRIDO[2,3-D]PYRIMIDIN-5-YL)-;DTXSID10479389

Suppliers and Price of 4-(6-Acetyl-1,3,7-trimethyl-2,4-dioxo-1,2,3,4,5,8-hexahydropyrido[2,3-D]pyrimidin-5-YL)benzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
4-(6-ACETYL-1,3,7-TRIMETHYL-2,4-DIOXO-1,2,3,4,5,8-HEXAHYDROPYRIDO-[2,3-D]PYRIMIDIN-5-YL)BENZOIC ACID 95.00%
5MG
$ 502.55

Total 3 raw suppliers

Chemical Property of 4-(6-Acetyl-1,3,7-trimethyl-2,4-dioxo-1,2,3,4,5,8-hexahydropyrido[2,3-D]pyrimidin-5-YL)benzoic acid

Chemical Property:

PSA：110.40000
LogP:1.34060
XLogP3:0.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:369.13247072
Heavy Atom Count:27
Complexity:789

Purity/Quality:

99% ^*data from raw suppliers

4-(6-ACETYL-1,3,7-TRIMETHYL-2,4-DIOXO-1,2,3,4,5,8-HEXAHYDROPYRIDO-[2,3-D]PYRIMIDIN-5-YL)BENZOIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C(C2=C(N1)N(C(=O)N(C2=O)C)C)C3=CC=C(C=C3)C(=O)O)C(=O)C

Technology Process of 4-(6-Acetyl-1,3,7-trimethyl-2,4-dioxo-1,2,3,4,5,8-hexahydropyrido[2,3-D]pyrimidin-5-YL)benzoic acid

There total 2 articles about 4-(6-Acetyl-1,3,7-trimethyl-2,4-dioxo-1,2,3,4,5,8-hexahydropyrido[2,3-D]pyrimidin-5-YL)benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 6642-31-5
6-Amino-1,3-dimethylbarbituric acid

: 619-66-9
4-Carboxybenzaldehyde

: 123-54-6,81235-32-7
acetylacetone

: 848029-08-3
4-(6-acetyl-1,3,7-trimethyl-2,4-dioxo-1,2,3,4,5,8-hexahydro-pyrido[2,3-d]pyrimidin-5-yl)-benzoic acid

Guidance literature:: 4-Carboxybenzaldehyde; Wang resin; With dmap; diisopropyl-carbodiimide; In 1-methyl-pyrrolidin-2-one; for 0.25h; microwave irradiation;

6-Amino-1,3-dimethylbarbituric acid; acetylacetone; With acetic acid; for 0.0666667h; microwave irradiation;

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 0.5h;
DOI:10.1016/j.tetlet.2004.12.109