2-(2-propen-1-yloxy)-5-methylacetophenone

Base Information

• Chemical Name: 2-(2-propen-1-yloxy)-5-methylacetophenone
• CAS No.: 108293-71-6
• Molecular Formula: C₁₂H₁₄O₂
• Molecular Weight: 190.242
• Mol file: 108293-71-6.mol

Synonyms:2-(2-propen-1-yloxy)-5-methylacetophenone

Chemical Property of 2-(2-propen-1-yloxy)-5-methylacetophenone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(2-propen-1-yloxy)-5-methylacetophenone

There total 2 articles about 2-(2-propen-1-yloxy)-5-methylacetophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

5-methyl-2-hydroxyacetophenone (1450-72-2) + allyl bromide (106-95-6) → 2-(2-propen-1-yloxy)-5-methylacetophenone (108293-71-6)

Guidance literature:

With potassium carbonate; In acetone; for 72h; Heating;

DOI:10.1021/jo00388a018

Reference yield:

1-(2-Allyloxy-5-methyl-phenyl)-ethanone oxime → 2-(2-propen-1-yloxy)-5-methylacetophenone (108293-71-6) + 4-Methyl-8,12-dioxa-13-aza-tricyclo[8.3.1.02,7]tetradeca-1(13),2(7),3,5-tetraen-14-one

Guidance literature:

With hydroxy(tosyloxy)iodobenzene; In acetonitrile; for 6h; Yield given. Yields of byproduct given; Ambient temperature;

DOI:10.1016/S0040-4039(98)00205-6

Reference yield: 99.0%

2-(2-propen-1-yloxy)-5-methylacetophenone (108293-71-6) → 1-(2-allyloxy-5-methylphenyl)ethanol

Guidance literature:

With sodium tetrahydroborate; In methanol; at 0 ℃;

DOI:10.1021/acs.orglett.9b00878

upstream raw materials:

5-methyl-2-hydroxyacetophenone

allyl bromide

Downstream raw materials:

1-<2-hydroxy-5-methyl-3-(2-propenyl)phenyl>-1-ethanone

1-<2-methoxy-5-methyl-3-(2-propenyl)phenyl>-1-ethanone

3,3'-(3,5-dimethyl-2,6-pyridinediyl)bis(2-methoxy-5-methylbenzenemethanol)

2,6-bis<3-(bromomethyl)-2-methoxy-5-methylphenyl>-3,5-dimethylpyridine