6-Benzyl-2,6-diazaspiro[3.4]octane

Base Information

Chemical Name:6-Benzyl-2,6-diazaspiro[3.4]octane
CAS No.:135380-28-8
Molecular Formula:C13H18N2
Molecular Weight:202.299
Hs Code.:2933990090
DSSTox Substance ID:DTXSID10568308
Wikidata:Q82454526
Mol file:135380-28-8.mol

Synonyms:6-BENZYL-2,6-DIAZASPIRO[3.4]OCTANE;135380-28-8;2,6-Diazaspiro[3.4]octane,6-(phenylmethyl)-;ZINCCARBONATEBASIC;SCHEMBL4292159;DTXSID10568308;FEEPYEXHXJWMAX-UHFFFAOYSA-N;AMY41206;MFCD08234736;AKOS015910769;MB05681;6-Benzyl-2,6-diaza-spiro[3.4]octane;WS-01262;CS-0000663;EN300-300052;6-(PHENYLMETHYL)-2,6-DIAZASPIRO[3.4]OCTANE;F2147-3195

Suppliers and Price of 6-Benzyl-2,6-diazaspiro[3.4]octane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynChem
6-BENZYL-2,6-DIAZASPIRO[3.4]OCTANE 95%
1 g
$ 477.00

Crysdot
6-Benzyl-2,6-diazaspiro[3.4]octane 95+%
1g
$ 589.00

Chemenu
6-benzyl-2,6-diazaspiro[3.4]octane 95%
1g
$ 557.00

American Custom Chemicals Corporation
6-BENZYL-2,6-DIAZASPIRO[3.4]OCTANE 98.00%
5MG
$ 496.50

Alichem
6-Benzyl-2,6-diazaspiro[3.4]octane
250mg
$ 417.13

AK Scientific
6-Benzyl-2,6-diazaspiro[3.4]octane
2.5g
$ 2733.00

Activate Scientific
6-Benzyl-2,6-diazaspiro[3.4]octane 95+%
1 g
$ 1310.00

Total 26 raw suppliers

Chemical Property of 6-Benzyl-2,6-diazaspiro[3.4]octane

Chemical Property:

Vapor Pressure:0.00081mmHg at 25°C
Refractive Index:1.603
Boiling Point:305.7 °C at 760 mmHg
Flash Point:128.7 °C
PSA：15.27000
Density:1.11 g/cm³
LogP:1.74860
Storage Temp.:2-8°C(protect from light)
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:202.146998583
Heavy Atom Count:15
Complexity:217

Purity/Quality:

97% ^*data from raw suppliers

6-BENZYL-2,6-DIAZASPIRO[3.4]OCTANE 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CN(CC12CNC2)CC3=CC=CC=C3

Technology Process of 6-Benzyl-2,6-diazaspiro[3.4]octane

There total 6 articles about 6-Benzyl-2,6-diazaspiro[3.4]octane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 135380-27-7
6-benzyl-2-(4-methylbenzenesulfonyl)-2,6-diazaspiro[3.4]octane

: 135380-28-8
6-benzyl-2,6-diazaspiro[3.4]octane

Guidance literature:: With sodium bis(2-methoxyethoxy)aluminium dihydride; In tetrahydrofuran; toluene; at 100 ℃; for 3h; Reagent/catalyst; Solvent;
DOI:10.1055/s-0034-1378722

Reference yield:

: 6-benzyl-2-(2-nitrobenzenesulfonyl)-2,6-diazaspiro[3.4]octane

: 135380-28-8
6-benzyl-2,6-diazaspiro[3.4]octane

Guidance literature:: With caesium carbonate; thiophenol; In acetonitrile; at 20 ℃; for 3h;
DOI:10.1055/s-0034-1378722

Reference yield:

: 17012-21-4
1-benzylpyrrolidine-3-carboxylic acid methyl ester

: 135380-28-8
6-benzyl-2,6-diazaspiro[3.4]octane

Guidance literature:: Multi-step reaction with 5 steps

1.1: lithium diisopropyl amide / tetrahydrofuran; hexane / 1 h / -70 °C

1.2: 0.5 h / -70 °C

2.1: lithium aluminium tetrahydride / tetrahydrofuran / 0.25 h / 0 °C

3.1: triethylamine / dichloromethane / 20 h / 20 °C

4.1: potassium carbonate / N,N-dimethyl-formamide / 20 h / 100 °C

5.1: sodium bis(2-methoxyethoxy)aluminium dihydride / tetrahydrofuran; toluene / 3 h / 100 °C

With lithium aluminium tetrahydride; potassium carbonate; triethylamine; sodium bis(2-methoxyethoxy)aluminium dihydride; lithium diisopropyl amide; In tetrahydrofuran; hexane; dichloromethane; N,N-dimethyl-formamide; toluene;
DOI:10.1055/s-0034-1378722