4-ISOTHIAZOL-5-YLPHENOL

Base Information

• Chemical Name: 4-ISOTHIAZOL-5-YLPHENOL
• CAS No.: 68535-60-4
• Molecular Formula: C9H7 N O S
• Molecular Weight: 177.22298
• Hs Code.: 2934999090
• Mol file: 68535-60-4.mol

Synonyms:

Chemical Property of 4-ISOTHIAZOL-5-YLPHENOL

Chemical Property:

• PSA: 61.36000
• LogP: 2.51570
• Storage Temp.: 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

4-(Isothiazol-5-yl)phenol 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-ISOTHIAZOL-5-YLPHENOL

There total 1 articles about 4-ISOTHIAZOL-5-YLPHENOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-(4-methoxy-phenyl)-isothiazole (10514-28-0) → 4-isothiazol-5-yl-phenol (68535-60-4)

Guidance literature:

With hydrogen bromide; Heating;

DOI:10.1021/jm00209a002

Reference yield:

4-isothiazol-5-yl-phenol (68535-60-4) + carbon dioxide (124-38-9,18923-20-1) → 2-hydroxy-5-isothiazol-5-yl-benzoic acid (68535-43-3)

Guidance literature:

With potassium carbonate; at 225 ℃; for 8h; under 230131 Torr;

DOI:10.1021/jm00209a002

upstream raw materials:

5-(4-methoxy-phenyl)-isothiazole

Downstream raw materials:

2-hydroxy-5-isothiazol-5-yl-benzoic acid

Refernces