68535-43-3

Basic information

• Product Name: 2-hydroxy-5-isothiazol-5-yl-benzoic acid
• Synonyms: 2-hydroxy-5-isothiazol-5-yl-benzoic acid
• CAS NO: 68535-43-3
• Molecular Weight: 221.236
• Mol File: 68535-43-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-hydroxy-5-isothiazol-5-yl-benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-hydroxy-5-isothiazol-5-yl-benzoic acid(68535-43-3)
• EPA Substance Registry System: 2-hydroxy-5-isothiazol-5-yl-benzoic acid(68535-43-3)

Safety Data

• Hazardous Substances Data: 68535-43-3(Hazardous Substances Data)

Upstream product

• 68535-60-4 4-isothiazol-5-yl-phenol 
• 124-38-9 carbon dioxide 
• 10514-28-0 5-(4-methoxy-phenyl)-isothiazole 

Relevant articles and documents

Synthesis and analgesic-antiinflammatory activity of some 4- and 5-substituted heteroarylsalicylic acids

We have made a series of 4- and 5-aryl- and 4- and 5-heteroarylsalicylic acid derivatives with the objective of reducing gastric irritation and increasing potency. Here we describe a series of 4- and 5-heterocyclic salicylic acids and their antiinflammatory-analgesic potencies measured in comparison to aspirin. An improvement of the therapeutic index over aspirin of 100 was achieved; however, the heterocyclic salicylic acids lacked antipyretic activity. Some physicochemical parameters which may bear on the antiinflammatory activity of these compounds are discussed.