C₃₅H₄₄N₄O₅

Base Information

Chemical Name:C₃₅H₄₄N₄O₅
CAS No.:1377324-65-6
Molecular Formula:C₃₅H₄₄N₄O₅
Molecular Weight:600.758
Hs Code.:

C<sub>35</sub>H<sub>44</sub>N<sub>4</sub>O<sub>5</sub>

Synonyms:C₃₅H₄₄N₄O₅

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Chemical Property of C₃₅H₄₄N₄O₅

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Technology Process of C₃₅H₄₄N₄O₅

There total 2 articles about C₃₅H₄₄N₄O₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 5.4%

: 880563-54-2
C₁₇H₂₅NO₄

: 35661-40-6
N-Fmoc L-Phe

: 1377324-65-6
C₃₅H₄₄N₄O₅

Guidance literature:: N-Fmoc L-Phe; With piperidine; Fmoc-Rink-(4-methylbenzhydrylamine) resin; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; for 2h; solid phase reaction;

With piperidine; In N,N-dimethyl-formamide; solid phase reaction;

C₁₇H₂₅NO₄; Further stages;
DOI:10.1016/j.bmcl.2012.03.048

Reference yield:

: 13565-36-1
1-(heptyloxy)-4-nitrobenzene

: 1377324-65-6
C₃₅H₄₄N₄O₅

Guidance literature:: Multi-step reaction with 3 steps

1.1: palladium on activated charcoal; hydrogen / methanol / 16 h / 20 °C

2.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 3 h / 20 °C

3.1: piperidine; Fmoc-Rink-(4-methylbenzhydrylamine) resin; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 2 h / solid phase reaction

3.2: solid phase reaction

With piperidine; Fmoc-Rink-(4-methylbenzhydrylamine) resin; palladium on activated charcoal; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; hydrogen; N-ethyl-N,N-diisopropylamine; In methanol; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2012.03.048