Technology Process of (1S,3S)-3-(benzyloxymethyl)cyclopentanol
There total 8 articles about (1S,3S)-3-(benzyloxymethyl)cyclopentanol which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
sodium acetate; toluene-4-sulfonic acid hydrazide;
In
1,4-dioxane; water;
for 4h;
Reflux;
DOI:10.1002/ejoc.201001473
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: potassium tert-butylate / N,N-dimethyl-formamide / 1 h / Reflux
2.1: di-isopropyl azodicarboxylate; triphenylphosphine / diethyl ether / 0.5 h / 0 °C / Inert atmosphere
2.2: 0 - 20 °C / Inert atmosphere
2.3: 6 h / 20 °C / Inert atmosphere
3.1: sodium acetate; toluene-4-sulfonic acid hydrazide / 1,4-dioxane; water / 4 h / Reflux
With
di-isopropyl azodicarboxylate; potassium tert-butylate; sodium acetate; toluene-4-sulfonic acid hydrazide; triphenylphosphine;
In
1,4-dioxane; diethyl ether; water; N,N-dimethyl-formamide;
2.1: Mitsunobu reaction / 2.2: Mitsunobu reaction;
DOI:10.1002/ejoc.201001473
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: 9-bora-bicyclo[3.3.1]nonane / tetrahydrofuran / 0 - 20 °C / Inert atmosphere
1.2: oxone / 6 h / 0 °C
2.1: potassium tert-butylate / N,N-dimethyl-formamide / 1 h / Reflux
3.1: di-isopropyl azodicarboxylate; triphenylphosphine / diethyl ether / 0.5 h / 0 °C / Inert atmosphere
3.2: 0 - 20 °C / Inert atmosphere
3.3: 6 h / 20 °C / Inert atmosphere
4.1: sodium acetate; toluene-4-sulfonic acid hydrazide / 1,4-dioxane; water / 4 h / Reflux
With
di-isopropyl azodicarboxylate; potassium tert-butylate; sodium acetate; 9-bora-bicyclo[3.3.1]nonane; toluene-4-sulfonic acid hydrazide; triphenylphosphine;
In
tetrahydrofuran; 1,4-dioxane; diethyl ether; water; N,N-dimethyl-formamide;
1.1: Hydroboration reaction / 3.1: Mitsunobu reaction / 3.2: Mitsunobu reaction;
DOI:10.1002/ejoc.201001473
