H-SER-PHE-LEU-LEU-ARG-ASN-NH2

Base Information

• Chemical Name: H-SER-PHE-LEU-LEU-ARG-ASN-NH2
• CAS No.: 141923-40-2
• Molecular Formula: C₃₄H₅₇N₁₁O₈
• Molecular Weight: 747.895
• Mol file: 141923-40-2.mol

Synonyms:17: PN:WO0181408 SEQID: 25 claimed protein; 5: PN: WO0015243 PAGE: 47 claimed protein

Chemical Property of H-SER-PHE-LEU-LEU-ARG-ASN-NH2

Chemical Property:

• PSA: 339.83000
• LogP: 1.93520
• Storage Temp.: −20°C
• Solubility.: acetonitrile: water (1:1): soluble

Purity/Quality:

99%, ^*data from raw suppliers

Ser-Phe-Leu-Leu-Arg-Asn-amide trifluoroacetate salt ≥98% (HPLC), film ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Ser-Phe-Leu-Leu-Arg-Asn-amide trifluoroacetate salt has been used as a protease-activated receptor 1 (PAR-1) selective activating peptide.

Technology Process of H-SER-PHE-LEU-LEU-ARG-ASN-NH2

There total 2 articles about H-SER-PHE-LEU-LEU-ARG-ASN-NH2 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-tert-butoxycarbonyl-L-leucine (13139-15-6,53296-34-7) + N-tert-butyloxycarbonylasparagine (7536-55-2) + N-tert-butoxycarbonyl-L-phenylalanine (13734-34-4) + Boc-Arg(Tos)-OH (13836-37-8) → TRAP-6 (141923-40-2)

Guidance literature:

Multistep reaction;

DOI:10.1021/jm00020a029

Reference yield:

N-tert-butoxycarbonyl-L-leucine (13139-15-6,53296-34-7) + t-butyloxycarbonyl-L-arginine (13726-76-6,78603-12-0) + N-Fmoc L-Phe (35661-40-6) + L-asparaginamide hydrochloride (57471-69-9) → TRAP-6 (141923-40-2)

Guidance literature:

Yield given. Multistep reaction;

DOI:10.1021/jo970736n

upstream raw materials:

N-tert-butoxycarbonyl-L-leucine

t-butyloxycarbonyl-L-arginine

N-Fmoc L-Phe

L-asparaginamide hydrochloride

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