(Z)-2-benzamido-3-(4-chlorophenyl)acrylohydrazide

Base Information

• Chemical Name: (Z)-2-benzamido-3-(4-chlorophenyl)acrylohydrazide
• CAS No.: 1022086-40-3
• Molecular Formula: C₁₆H₁₄ClN₃O₂
• Molecular Weight: 315.759
• Mol file: 1022086-40-3.mol

Synonyms:(Z)-2-benzamido-3-(4-chlorophenyl)acrylohydrazide

Chemical Property of (Z)-2-benzamido-3-(4-chlorophenyl)acrylohydrazide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (Z)-2-benzamido-3-(4-chlorophenyl)acrylohydrazide

There total 3 articles about (Z)-2-benzamido-3-(4-chlorophenyl)acrylohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

(Z)-2-phenyl-4-(4-chlorobenzylidene)-5(4H)-oxazolone (15601-44-2,57427-77-7,57427-86-8) → (Z)-2-benzamido-3-(4-chlorophenyl)acrylohydrazide (1022086-40-3)

Guidance literature:

With hydrazine; In ethanol; at 20 ℃; for 3h;

Reference yield:

Hippuric Acid (495-69-2,140480-84-8,21251-67-2,91787-63-2,66407-11-2) → (Z)-2-benzamido-3-(4-chlorophenyl)acrylohydrazide (1022086-40-3)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic anhydride; sodium acetate / 2.5 h / 80 °C / Green chemistry

2: hydrazine hydrate / ethanol / 1.17 h / 20 °C / Green chemistry

With hydrazine hydrate; sodium acetate; acetic anhydride; In ethanol;

DOI:10.14233/ajchem.2014.16333

Reference yield:

4-chlorobenzaldehyde (104-88-1) → (Z)-2-benzamido-3-(4-chlorophenyl)acrylohydrazide (1022086-40-3)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic anhydride; sodium acetate / 2.5 h / 80 °C / Green chemistry

2: hydrazine hydrate / ethanol / 1.17 h / 20 °C / Green chemistry

With hydrazine hydrate; sodium acetate; acetic anhydride; In ethanol;

DOI:10.14233/ajchem.2014.16333

upstream raw materials:

(Z)-2-phenyl-4-(4-chlorobenzylidene)-5(4H)-oxazolone

Hippuric Acid

4-chlorobenzaldehyde