(S)-2-TETRAHYDROISOQUINOLINE ACETIC ACID HYDROCHLORIDE

Base Information

• Chemical Name: (S)-2-TETRAHYDROISOQUINOLINE ACETIC ACID HYDROCHLORIDE
• CAS No.: 270082-22-9
• Molecular Formula: C₁₁H₁₃NO₂
• Molecular Weight: 191.23
• Hs Code.: 2933499090
• Mol file: 270082-22-9.mol

Synonyms:(S)-2-TETRAHYDROISOQUINOLINE ACETIC ACID HCL;(S)-2-TETRAHYDROISOQUINOLINE ACETIC ACID HYDROCHLORIDE;H-TQA-OH HCL;H-TIC-(C*CH2)OH HCL;(S)-2-tetrahydroisoquinolineaceticacidCl;(S)-1,2,3,4-Tetrahydro-3-isoquinolineacetic acid hydrochloride;(S)-1,2,3,4-Tetrahydroisoquinoline-3-acetic acid hydrochloride, 95%

Chemical Property of (S)-2-TETRAHYDROISOQUINOLINE ACETIC ACID HYDROCHLORIDE

Chemical Property:

• Vapor Pressure: 1.02E-06mmHg at 25°C
• Boiling Point: 388°C at 760 mmHg
• PKA: 3.97±0.10(Predicted)
• Flash Point: 188.5°C
• PSA: 49.33000
• Density: 1.162±0.06 g/cm3(Predicted)
• LogP: 2.30640

Purity/Quality:

98%min ^*data from raw suppliers

(S)-2-TetrahydroisoquinolineAceticAcid ^*data from reagent suppliers

Safty Information:

• Statements: 36
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

• Uses: It is used as an active pharmaceutical intermediate. It is also an important organic intermediate used in agrochemicals, pharmaceuticals and dyestuff fields.

Technology Process of (S)-2-TETRAHYDROISOQUINOLINE ACETIC ACID HYDROCHLORIDE

There total 1 articles about (S)-2-TETRAHYDROISOQUINOLINE ACETIC ACID HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + (S)-3-amino-4-phenylbutanoic acid hydrochloride (138165-77-2,460039-42-3) → 2-(1,2,3,4-tetrahydroisoquinolin-3-yl)acetic acid (270082-22-9,187218-03-7)

Guidance literature:

With hydrogenchloride; In water; at 100 ℃; for 3h;

DOI:10.1016/j.ejmech.2020.112888

upstream raw materials:

formaldehyd

(S)-3-amino-4-phenylbutanoic acid hydrochloride

Refernces