2-(6-Chloropyridin-3-yl)acetic acid

Base Information

Chemical Name:2-(6-Chloropyridin-3-yl)acetic acid
CAS No.:39891-13-9
Molecular Formula:C7H6ClNO2
Molecular Weight:171.583
Hs Code.:2933399090
European Community (EC) Number:670-360-7
DSSTox Substance ID:DTXSID60555440
Nikkaji Number:J2.888.127D
Wikidata:Q72458625
Mol file:39891-13-9.mol

Synonyms:39891-13-9;2-(6-chloropyridin-3-yl)acetic acid;2-chloropyridine-5-acetic acid;(6-Chloro-pyridin-3-yl)-acetic acid;6-chloro-3-pyridineacetic acid;(6-chloropyridin-3-yl)acetic acid;3-PYRIDINEACETIC ACID, 6-CHLORO-;2-(2-Chloropyridin-5-yl)acetic acid;MFCD01863172;(2-Chloropyridyl)-5-aceticacid;2-(6-Chloropyridin-3-yl)aceticacid;SCHEMBL256024;2-chloro-5-pyridylacetic acid;6-chloropyridine-3-acetic acid;2-chloropyridin-5-ylacetic acid;6-chloropyrid-3-yl acetic acid;(2-Cloropyridyl)-5-acetic acid;(2-chloropyridyl)-5-acetic acid;DTXSID60555440;AMY31475;AKOS005255186;AC-6660;CS-W001177;PS-8686;NCGC00342849-01;SY041953;(6-CHLORO-3-PYRIDINYL)ACETIC ACID;A6663;EN300-73920;AB01334508-02;(6-chloro-pyridin-3-yl)-acetic acid, AldrichCPR;J-501672;Z1165304038;(6-CHLORO-PYRIDIN-3-YL)-ACETIC ACID

Suppliers and Price of 2-(6-Chloropyridin-3-yl)acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(2-Chloropyridin-5-yl)aceticacid
500mg
$ 65.00

TRC
2-(2-Chloropyridin-5-yl)aceticacid
250mg
$ 55.00

SynQuest Laboratories
2-Chloropyridin-5-ylacetic acid
5 g
$ 32.00

Matrix Scientific
2-Chloropyridine-5-acetic acid 98%
1g
$ 10.00

Matrix Scientific
2-Chloropyridine-5-acetic acid 98%
5g
$ 29.00

Matrix Scientific
2-Chloropyridine-5-acetic acid 98%
25g
$ 118.00

Crysdot
2-(6-Chloropyridin-3-yl)aceticacid 98%
100g
$ 297.00

Chemenu
2-Chloropyridine-5-aceticacid 98%
100g
$ 281.00

Biosynth Carbosynth
6-Chloro-3-pyridinylacetic acid
100 g
$ 550.00

Biosynth Carbosynth
6-Chloro-3-pyridinylacetic acid
50 g
$ 320.00

Total 85 raw suppliers

Chemical Property of 2-(6-Chloropyridin-3-yl)acetic acid

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:164-169 °C
Refractive Index:1.575
Boiling Point:336.613 °C at 760 mmHg
PKA:3.91±0.10(Predicted)
Flash Point:157.378 °C
PSA：50.19000
Density:1.406 g/cm³
LogP:1.36210
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:171.0087061
Heavy Atom Count:11
Complexity:151

Purity/Quality:

98% ^*data from raw suppliers

2-(2-Chloropyridin-5-yl)aceticacid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi,Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=NC=C1CC(=O)O)Cl

Technology Process of 2-(6-Chloropyridin-3-yl)acetic acid

There total 6 articles about 2-(6-Chloropyridin-3-yl)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 39891-09-3
(6-chloro-pyridin-3-yl)-acetonitrile

: 39891-13-9
2-(6-chloropyridin-3-yl)acetic acid

Guidance literature:: With hydrogenchloride; water; at 80 ℃; for 24h;

Reference yield: 74.3%

: 70258-18-3
2-chloro-5-(chloromethyl)pyridine

: 124-38-9,18923-20-1
carbon dioxide

: 39891-13-9
2-(6-chloropyridin-3-yl)acetic acid

Guidance literature:: In N,N-dimethyl-formamide; at 40 ℃; for 15h; under 22502.3 Torr; Autoclave;

Reference yield:

: 197376-47-9
ethyl (6-chloro-pyridin-3-yl)acetate

: 39891-13-9
2-(6-chloropyridin-3-yl)acetic acid

Guidance literature:: ethyl (6-chloro-pyridin-3-yl)acetate; With lithium hydroxide monohydrate; In 1,4-dioxane; water; at 0 - 25 ℃; for 12h;

With hydrogenchloride; In water;
DOI:10.1021/acs.jmedchem.1c00034