(S)-1,2-EPOXYPENTANE

Base Information

• Chemical Name: (S)-1,2-EPOXYPENTANE
• CAS No.: 123731-68-0
• Molecular Formula: C5H10 O
• Molecular Weight: 86.1338
• Mol file: 123731-68-0.mol

Synonyms:Oxirane,propyl-, (2S)- (9CI); Oxirane, propyl-, (S)-; (S)-1,2-Epoxypentane;(S)-Propyloxirane

Chemical Property of (S)-1,2-EPOXYPENTANE

Chemical Property:

• PSA: 12.53000
• LogP: 1.18530

Purity/Quality:

99% ^*data from raw suppliers

(S)-1,2-EPOXYPENTANE 98.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (S)-1,2-EPOXYPENTANE

There total 12 articles about (S)-1,2-EPOXYPENTANE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

(2R)-2-chloropentan-1-ol (139365-00-7) → (S)-1,2-epoxypentane (123731-68-0)

Guidance literature:

With potassium hydroxide; at 25 ℃; for 1h;

DOI:10.1002/hlca.200490237

Reference yield: 96.0%

→ (2R)-2-chloropentan-1-ol (139365-00-7) + (S)-1,2-epoxypentane (123731-68-0)

Guidance literature:

Reference yield: 47.0%

2-pentyloxirane (1003-14-1) → (S)-1,2-epoxypentane (123731-68-0)

Guidance literature:

With water; acetic acid; optical yield given as %ee;

DOI:10.1016/j.tet.2010.03.066

upstream raw materials:

(S)-(-)-1,2-pentanediol

2-pentyloxirane

(2R)-2-chloropentan-1-ol

1-penten

Downstream raw materials:

haliclamide

Methanesulfonic acid (S)-1-(2-bromo-3,4,5-trimethoxy-phenyl)-4-(tert-butyl-dimethyl-silanyloxy)-heptyl ester

1-<(4S)-4-t-butyldimethylsilyloxy-1-phenylthioheptyl>-3,4,5-trimethoxybenzene

Acetic acid (S)-1-(2-bromo-3,4,5-trimethoxy-phenyl)-4-(tert-butyl-dimethyl-silanyloxy)-heptyl ester

Refernces

• 1、 H?tling, Susann,Bittner, Celine,Tamm, Matthias,D?hn, Sonja,Collatz, Jana,Steidle, Johannes L. M.,Schulz, Stefan. "Identification of a Grain Beetle Macrolide Pheromone and Its Synthesis by Ring-Closing Metathesis Using a Terminal Alkyne". . p. 5004 - 5007. Retrieved 2015.
• 2、 Plazinska, Anita,Pajak, Karolina,Rutkowska, Ewelina,Jimenez, Lucita,Kozocas, Joseph,Koolpe, Gary,Tanga, Mary,Toll, Lawrence,Wainer, Irving W.,Jozwiak, Krzysztof. "Comparative molecular field analysis of fenoterol derivatives interacting with an agonist-stabilized form of the β2-adrenergic receptor". . p. 234 - 246. Retrieved 2014/01/17.
• 3、 Cui, Yubo,Tu, Wangyang,Floreancig, Paul E.. "Total synthesis of neopeltolide and analogs". scheme or table. p. 4867 - 4873. Retrieved 2010/08/06.