BLOOD GROUP H DISACCHARIDE

Base Information

• Chemical Name: BLOOD GROUP H DISACCHARIDE
• CAS No.: 146076-26-8
• Molecular Formula: C₁₂H₂₂O₁₀
• Molecular Weight: 326.301
• Mol file: 146076-26-8.mol

Synonyms:FUC1-A-2GAL;FUC-(ALPHA1-2)GAL;H-DISACCHARIDE;BLOOD GROUP H DISACCHARIDE;2-O-(A-L-FUCOPYRANOSYL)-D-GALACTOSE;2-O-(alpha-L-Fucopyranosyl)-D-galactose;H-Disaccharide, Fuc1-a-2Gal;2-O-(α-L-Fucopyranosyl)-D-galactose

Chemical Property of BLOOD GROUP H DISACCHARIDE

Chemical Property:

• Melting Point: 125 - 126 °C
• Boiling Point: 633.9±55.0 °C(Predicted)
• PKA: 11.91±0.70(Predicted)
• PSA: 169.30000
• Density: 1.66±0.1 g/cm3(Predicted)
• LogP: -4.36960

Purity/Quality:

98%Min ^*data from raw suppliers

2-O-(α-L-Fucopyranosyl)-D-galactose ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of BLOOD GROUP H DISACCHARIDE

There total 15 articles about BLOOD GROUP H DISACCHARIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.9%

benzyl 2-O-α-L-rhamnopyranosyl-β-D-galactopyranoside (80832-23-1) → 2-O-α-L-rhamnopyranosyl-D-galactopyranose (2781-65-9,16741-18-7,19949-48-5,36476-16-1,80876-56-8,137171-16-5,137171-17-6,137171-18-7,137171-19-8,146076-26-8)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol; water; acetic acid; for 12h; Ambient temperature;

DOI:10.1016/S0008-6215(00)80970-2

Reference yield:

rhamnosyl-(1<*>2)-O-6)> glucose (131279-12-4) → neohesperidose (2781-65-9,16741-18-7,19949-48-5,36476-16-1,80876-56-8,137171-16-5,137171-17-6,137171-18-7,137171-19-8,146076-26-8) + rutinose (552-74-9,26184-96-3,47235-47-2,56906-86-6,56942-81-5,59246-67-2,68398-81-2,68567-48-6,68567-49-7,75828-90-9)

Guidance literature:

With sulfuric acid; In ethanol; water; for 0.25h; Product distribution; hydrolysis for structure determination;

Reference yield:

clitorin (55804-74-5,109008-28-8) → rhamnosyl-(1<*>2)-O-6)> glucose (131279-12-4) + neohesperidose (2781-65-9,16741-18-7,19949-48-5,36476-16-1,80876-56-8,137171-16-5,137171-17-6,137171-18-7,137171-19-8,146076-26-8) + rutinose (552-74-9,26184-96-3,47235-47-2,56906-86-6,56942-81-5,59246-67-2,68398-81-2,68567-48-6,68567-49-7,75828-90-9)

Guidance literature:

With sulfuric acid; In ethanol; water; for 3h; Product distribution; hydrolysis products were identified as their trimethylsilyl derivatives by GC-MS;

upstream raw materials:

benzyl 2-O-α-L-rhamnopyranosyl-β-D-galactopyranoside

sophoraflavoside I

benzyl 3-O-benzoyl-4,6-O-benzylidene-β-D-galactopyranoside

benzyl 4,6-O-benzylidene-2-O-α-L-rhamnopyranosyl-β-D-galactopyranoside

Downstream raw materials:

L-Rhamnose

D-Galactose

Acetic acid (3R,4S,5S,6R)-2,5-diacetoxy-6-acetoxymethyl-3-((2S,3R,4R,5S,6S)-3,4,5-triacetoxy-6-methyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-4-yl ester

Refernces

• 1、 Liptak Andras,Szurmai Zoltan,Nanasi Pal. "SYNTHESIS OF 2-O-α, 3-O-α, 3-O-β, AND 4-O-α-L-RHAMNOPYRANOSYL-D-GALACTOSE". . p. 13 - 22. Retrieved 2007/10/02.
• 2、 Kamiya,Esaki,Konishi. "Synthesis of some new α and β (1→2) linked disaccharides containing l quinovose (6 deoxy l glucose)". . p. 273 - 276. Retrieved 2007/10/11.