3-Fluoronaphthalene-2-carbaldehyde

Base Information

Chemical Name:3-Fluoronaphthalene-2-carbaldehyde
CAS No.:21597-61-5
Molecular Formula:C₁₁H₇FO
Molecular Weight:174.174
Hs Code.:
DSSTox Substance ID:DTXSID90504921
Wikidata:Q82359706
Mol file:21597-61-5.mol

Synonyms:21597-61-5;3-Fluoro-2-naphthaldehyde;3-fluoronaphthalene-2-carbaldehyde;3-Fluoro-naphthalene-2-carboxaldehyde;SCHEMBL13830984;DTXSID90504921;MFCD17012235;AKOS022638835;SY275318;FT-0759518;E70294;F1911-3810

Suppliers and Price of 3-Fluoronaphthalene-2-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Alichem
3-Fluoronaphthalene-2-carboxaldehyde
1g
$ 1819.80

Alichem
3-Fluoronaphthalene-2-carboxaldehyde
500mg
$ 1029.00

Total 6 raw suppliers

Chemical Property of 3-Fluoronaphthalene-2-carbaldehyde

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:174.048093005
Heavy Atom Count:13
Complexity:193

Purity/Quality:

98%+ ^*data from raw suppliers

3-Fluoronaphthalene-2-carboxaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C2C=C(C(=CC2=C1)C=O)F
Uses 3-Fluoro-2-naphthaldehyde is a reagent used in the catalytic nucleophilic addition to aromatic carbonyl compounds.

Technology Process of 3-Fluoronaphthalene-2-carbaldehyde

There total 5 articles about 3-Fluoronaphthalene-2-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.5%

: 1718-17-8
2-carbomethoxy-3-fluoronaphthalene

: 21597-61-5
2-fluoro-3-naphthaldehyde

Guidance literature:: With diisobutylaluminium hydride; In toluene; at -78 ℃; for 0.5h;
DOI:10.1021/jm300043c

Reference yield: 34.0%

: 66-99-9
β-naphthaldehyde

: 21597-61-5
2-fluoro-3-naphthaldehyde

Guidance literature:: β-naphthaldehyde; With n-butyllithium; N,N',N'-trimethylenediamine; In tetrahydrofuran; hexane; at -20 ℃; for 24h;

With N-fluorobis(benzenesulfon)imide; In tetrahydrofuran; hexane;
DOI:10.1002/anie.202008358

Reference yield:

: 21597-54-6
Methyl 3-amino-2-naphthoate

: 21597-61-5
2-fluoro-3-naphthaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1.1: tetrafluoroboric acid; sodium nitrite / water / 0.33 h / -15 - 0 °C

1.2: 3 h / Reflux

2.1: diisobutylaluminium hydride / toluene / 0.5 h / -78 °C

With tetrafluoroboric acid; diisobutylaluminium hydride; sodium nitrite; In water; toluene;
DOI:10.1021/jm300043c