Technology Process of 1,3,3-trimethyl-2-(3,4,5-trimethoxyphenyl)-4-methylenepiperidine
There total 8 articles about 1,3,3-trimethyl-2-(3,4,5-trimethoxyphenyl)-4-methylenepiperidine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
In
tetrahydrofuran; diethyl ether;
for 24h;
Heating;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 81 percent / zinc / various solvent(s) / 1. reflux, 45 min.; 2. r.t., 48h;
2: 94 percent / HCl(g) / ethanol / 24 h / 55 - 60 °C
3: 71 percent Turnov. / acetic acid / 16 h / 100 °C
4: 61 percent / sodium hydride / benzene / 4 h / Heating
5: 22 percent / 50percent hydrochloric acid / 2.5 h / Heating
6: 92 percent / diethyl ether; tetrahydrofuran / 24 h / Heating
With
hydrogenchloride; sodium hydride; acetic acid; zinc;
In
tetrahydrofuran; diethyl ether; ethanol; benzene;
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 99 percent / benzene / 1. 4h; 2. reflux
2: 81 percent / zinc / various solvent(s) / 1. reflux, 45 min.; 2. r.t., 48h;
3: 94 percent / HCl(g) / ethanol / 24 h / 55 - 60 °C
4: 71 percent Turnov. / acetic acid / 16 h / 100 °C
5: 61 percent / sodium hydride / benzene / 4 h / Heating
6: 22 percent / 50percent hydrochloric acid / 2.5 h / Heating
7: 92 percent / diethyl ether; tetrahydrofuran / 24 h / Heating
With
hydrogenchloride; sodium hydride; acetic acid; zinc;
In
tetrahydrofuran; diethyl ether; ethanol; benzene;
