(1S,5S)-4,4,8-trimethyl-2-phenyl-3-azabicyclo[3.3.1]nona-2,7-diene

Base Information

• Chemical Name: (1S,5S)-4,4,8-trimethyl-2-phenyl-3-azabicyclo[3.3.1]nona-2,7-diene
• CAS No.: 1583272-65-4
• Molecular Formula: C₁₇H₂₁N
• Molecular Weight: 239.36
• Mol file: 1583272-65-4.mol

Synonyms:(1S,5S)-4,4,8-trimethyl-2-phenyl-3-azabicyclo[3.3.1]nona-2,7-diene

Chemical Property of (1S,5S)-4,4,8-trimethyl-2-phenyl-3-azabicyclo[3.3.1]nona-2,7-diene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of (1S,5S)-4,4,8-trimethyl-2-phenyl-3-azabicyclo[3.3.1]nona-2,7-diene

There total 1 articles about (1S,5S)-4,4,8-trimethyl-2-phenyl-3-azabicyclo[3.3.1]nona-2,7-diene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

beta-pinene (18172-67-3,19902-08-0,25719-60-2) + benzonitrile (100-47-0) → (1S,5S)-4,4,8-trimethyl-2-phenyl-3-azabicyclo[3.3.1]nona-2,7-diene (1583272-65-4) + N-((1S,5S,6S)-2,2,6-trimethyl-4-phenyl-3-azabicyclo[3.3.1]non-3-en-6-yl)benzamide

Guidance literature:

beta-pinene; benzonitrile; With sulfuric acid; In benzene; at 0 - 20 ℃; for 24.5h;

With water; In diethyl ether; benzene; for 0.166667h; stereoselective reaction;

DOI:10.1007/s00706-014-1185-x

Reference yield: 80.0%

(1S,5S)-4,4,8-trimethyl-2-phenyl-3-azabicyclo[3.3.1]nona-2,7-diene (1583272-65-4) → (1S,4S,5S)-2,2,6-trimethyl-4-phenyl-3-azabicyclo[3.3.1]non-6-ene

Guidance literature:

With sodium tetrahydroborate; In methanol; at 0 - 20 ℃; stereospecific reaction;

DOI:10.1016/j.tet.2016.11.057

upstream raw materials:

beta-pinene

benzonitrile