C₂₂H₂₃ClF₂O₇S₂

Base Information

• Chemical Name: C₂₂H₂₃ClF₂O₇S₂
• CAS No.: 1100361-45-2
• Molecular Formula: C₂₂H₂₃ClF₂O₇S₂
• Molecular Weight: 537.002
• Mol file: 1100361-45-2.mol

Synonyms:C₂₂H₂₃ClF₂O₇S₂

Chemical Property of C₂₂H₂₃ClF₂O₇S₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₂H₂₃ClF₂O₇S₂

There total 12 articles about C₂₂H₂₃ClF₂O₇S₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

C27H25ClF2O7S2 (1100361-35-0) + 2-hydroxyethanethiol (60-24-2) → C22H23ClF2O7S2 (1100361-45-2)

Guidance literature:

C₂₇H₂₅ClF₂O₇S₂; 2-hydroxyethanethiol; With potassium hydroxide; In ethanol;

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane;

DOI:10.1016/j.bmcl.2016.04.095

Reference yield:

C20H19ClF2O5S (1100361-34-9) → C22H23ClF2O7S2 (1100361-45-2)

Guidance literature:

Multi-step reaction with 3 steps

1: triethylamine

2: potassium hydroxide / ethanol / 70 °C

3: 3-chloro-benzenecarboperoxoic acid / dichloromethane

With triethylamine; 3-chloro-benzenecarboperoxoic acid; potassium hydroxide; In ethanol; dichloromethane;

DOI:10.1016/j.bmcl.2012.11.047

Reference yield:

2-[(4-chloro-phenylsulfanyl)-(2,3,6-trifluoro-phenyl)-methyl]-propane-1,3-diol (944950-53-2) → C22H23ClF2O7S2 (1100361-45-2)

Guidance literature:

Multi-step reaction with 12 steps

1: potassium tert-butylate / tetrahydrofuran

2: Dess-Martin periodane / dichloromethane

3: trimethylsilyl trifluoromethanesulfonate

4: boron trifluoride diethyl etherate / dichloromethane

5: oxone / acetone; water

6: triethylamine / dichloromethane

7: potassium tert-butylate / tetrahydrofuran

8: ozone / dichloromethane

9: Resolution of racemate

10: triethylamine

11: potassium hydroxide / ethanol / 70 °C

12: 3-chloro-benzenecarboperoxoic acid / dichloromethane

With oxone; trimethylsilyl trifluoromethanesulfonate; boron trifluoride diethyl etherate; potassium tert-butylate; Dess-Martin periodane; ozone; triethylamine; 3-chloro-benzenecarboperoxoic acid; potassium hydroxide; In tetrahydrofuran; ethanol; dichloromethane; water; acetone;

DOI:10.1016/j.bmcl.2012.11.047

upstream raw materials:

2-[(4-chloro-phenylsulfanyl)-(2,3,6-trifluoro-phenyl)-methyl]-propane-1,3-diol

2-[(4-chloro-phenylsulfanyl)-(2,3,6-trifluoro-phenyl)-methyl]-malonic acid dimethyl ester

C₂₀H₁₉ClF₂O₅S

C₂₇H₂₅ClF₂O₇S₂

Downstream raw materials:

C₂₅H₂₅ClF₂N₂O₆S₂

C₂₆H₂₈ClF₂NO₇S₂

C₂₂H₂₁ClF₂O₆S₂

C₂₆H₃₂ClF₂NO₆S₂