thymidine 5'-(2-deoxy-α-D-glucopyranosyl diphosphate)

Base Information

• Chemical Name: thymidine 5'-(2-deoxy-α-D-glucopyranosyl diphosphate)
• CAS No.: 289902-34-7
• Molecular Formula: C₁₆H₂₆N₂O₁₅P₂
• Molecular Weight: 548.334
• Mol file: 289902-34-7.mol

Synonyms:thymidine 5'-(2-deoxy-α-D-glucopyranosyl diphosphate)

Chemical Property of thymidine 5'-(2-deoxy-α-D-glucopyranosyl diphosphate)

Chemical Property:

Purity/Quality:

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MSDS Files:

Useful:

Technology Process of thymidine 5'-(2-deoxy-α-D-glucopyranosyl diphosphate)

There total 1 articles about thymidine 5'-(2-deoxy-α-D-glucopyranosyl diphosphate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-deoxy-6-phosphate-glucose (27638-67-1) + thymidine 5'-phosphate (365-07-1,15108-71-1,60363-32-8,96744-88-6,132696-16-3,143838-77-1) → thymidine 5'-(2-deoxy-α-D-glucopyranosyl diphosphate) (289902-34-7)

Guidance literature:

With glucosee 1,6-diphosphate; acetylphosphoric acid; recombinant acetate kinase from Escherichia coli K₁₂; recombinant phosphomannomutase from Escherichia coli K₁₂; recombinant TDP-glucose synthase from Escherichia coli K₁₂; recombinant TMP kinase from Escherichia coli K₁₂; ATP; magnesium chloride; at 37 ℃; for 3h; Heating;

DOI:10.1016/j.molcatb.2009.11.008

Reference yield:

thymidine 5'-(2-deoxy-α-D-glucopyranosyl diphosphate) (289902-34-7) + 3,4-dichlorophenol (95-77-2) → C12H14Cl2O5

Guidance literature:

With glycosyltransferases YdhE bacillus licheniformi; magnesium chloride; In dimethyl sulfoxide; at 30 ℃; for 3h; pH=8.8; Reagent/catalyst; Enzymatic reaction;

DOI:10.1021/acs.orglett.9b03040

Reference yield:

thymidine 5'-(2-deoxy-α-D-glucopyranosyl diphosphate) (289902-34-7) + 3,4-dichlorothiophenol (5858-17-3) → C12H14Cl2O4S

Guidance literature:

With glycosyltransferases YdhE bacillus licheniformi; magnesium chloride; In dimethyl sulfoxide; at 30 ℃; for 3h; pH=8.8; Reagent/catalyst; Enzymatic reaction;

DOI:10.1021/acs.orglett.9b03040

upstream raw materials:

2-deoxy-6-phosphate-glucose

thymidine 5'-phosphate