tert-Butyl 2-(3-(3-(3,4-dimethoxyphenyl)propanoyl)phenoxy)acetate

Base Information

Chemical Name:tert-Butyl 2-(3-(3-(3,4-dimethoxyphenyl)propanoyl)phenoxy)acetate
CAS No.:178445-86-8
Molecular Formula:C23H28O6
Molecular Weight:400.472
Hs Code.:2918990090
DSSTox Substance ID:DTXSID70378006
Wikidata:Q82167431
Mol file:178445-86-8.mol

Synonyms:178445-86-8;tert-Butyl 2-(3-(3-(3,4-dimethoxyphenyl)propanoyl)phenoxy)acetate;Tert-butyl 2-[3-[3-(3,4-dimethoxyphenyl)propanoyl]phenoxy]acetate;1,1-Dimethylethyl [3-[3-(3,4-dimethoxyphenyl)-1-oxo-propyl]phenoxy]-acetate;MFCD06245368;SCHEMBL499701;DTXSID70378006;1-(3-(tert-Butoxycarbonylmethoxy)phenyl)-3-(3,4-dimethoxyphenyl)propan-1-one;AKOS005257470;AT11516;MS-20832;FT-0717725;A812371;A1-06723;tert-Butyl {3-[3-(3,4-dimethoxyphenyl)propanoyl]phenoxy}acetate;tert-Butyl2-(3-(3-(3,4-dimethoxyphenyl)propanoyl)phenoxy)acetate;1,1-Dimethylethyl [3-[3-(3,4-dimethoxyphenyl)-1-oxopropyl]phenoxy]acetate;COC1=C(OC)C=C(CCC(=O)C2=CC(OCC(=O)OC(C)(C)C)=CC=C2)C=C1;Acetic acid, 2-[3-[3-(3,4-dimethoxyphenyl)-1-oxopropyl]phenoxy]-, 1,1-dimethylethyl ester;Acetic acid,2-[3-[3-(3,4-dimethoxyphenyl)-1-oxopropyl]phenoxy]-,1,1-dimethylethyl ester

Suppliers and Price of tert-Butyl 2-(3-(3-(3,4-dimethoxyphenyl)propanoyl)phenoxy)acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
1,1-Dimethylethyl [3-[3-(3,4-dimethoxyphenyl)-1-oxo-propyl]phenoxy]-acetate 95%
5g
$ 1816.00

American Custom Chemicals Corporation
1,1-DIMETHYLETHYL [3-[3-(3,4-DIMETHOXYPHENYL)-1-OXO-PROPYL]PHENOXY]-ACETATE 95.00%
500MG
$ 859.82

A1 Biochem Labs
1,1-Dimethylethyl[3-[3-(3,4-dimethoxyphenyl)-1-oxo-propyl]phenoxy]-acetate 95%
5 g
$ 1100.00

Total 10 raw suppliers

Chemical Property of tert-Butyl 2-(3-(3-(3,4-dimethoxyphenyl)propanoyl)phenoxy)acetate

Chemical Property:

Vapor Pressure:5.43E-11mmHg at 25°C
Refractive Index:1.531
Boiling Point:521.9 °C at 760 mmHg
Flash Point:224.7 °C
PSA：71.06000
Density:1.124 g/cm³
LogP:4.23980
XLogP3:4.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:11
Exact Mass:400.18858861
Heavy Atom Count:29
Complexity:526

Purity/Quality:

97% ^*data from raw suppliers

1,1-Dimethylethyl [3-[3-(3,4-dimethoxyphenyl)-1-oxo-propyl]phenoxy]-acetate 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)COC1=CC=CC(=C1)C(=O)CCC2=CC(=C(C=C2)OC)OC

Technology Process of tert-Butyl 2-(3-(3-(3,4-dimethoxyphenyl)propanoyl)phenoxy)acetate

There total 9 articles about tert-Butyl 2-(3-(3-(3,4-dimethoxyphenyl)propanoyl)phenoxy)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 5292-43-3
bromoacetic acid tert-butyl ester

: 178445-83-5
3-(3,4-dimethoxyphenyl)-1-(3-hydroxyphenyl)-1-propanone

: 178445-86-8
2[[3-(3,4-dimethyoxyphenyl)-1-oxopropyl]phenoxy]acetic acid 1,1-dimethylester

Guidance literature:: With potassium carbonate; In acetone; at 20 ℃; for 16h; Inert atmosphere;
DOI:10.1021/acsmedchemlett.0c00272

Reference yield: 55.0%

: tert-butyl 2-{3-[3-(3,4-dimethoxyphenyl)-1-hydroxypropyl]phen-oxy}acetate

: 178445-86-8
2[[3-(3,4-dimethyoxyphenyl)-1-oxopropyl]phenoxy]acetic acid 1,1-dimethylester

Guidance literature:: With Dess-Martin periodane; In dichloromethane; at 20 ℃;

Reference yield:

: 121-71-1
3-Hydroxyacetophenone

: 178445-86-8
2[[3-(3,4-dimethyoxyphenyl)-1-oxopropyl]phenoxy]acetic acid 1,1-dimethylester

Guidance literature:: Multi-step reaction with 3 steps

1: 91 percent / aq. KOH / ethanol / 16 h / 20 °C

2: 76 percent / H₂ / Lindlar catalyst / aq. methanol / 6 h / 2068.59 - 2585.74 Torr

3: 99 percent / K₂CO₃ / acetone / 20 h / 20 °C

With potassium hydroxide; hydrogen; potassium carbonate; Lindlar's catalyst; In methanol; ethanol; acetone; 1: Condensation / 2: Hydrogenation / 3: Alkylation;
DOI:10.1016/S0968-0896(98)00125-4