tert-butyl N-[2-(1-hydroxyethyl)phenyl]carbamate

Base Information

Chemical Name:tert-butyl N-[2-(1-hydroxyethyl)phenyl]carbamate
CAS No.:328956-56-5
Molecular Formula:C13H19 N O3
Molecular Weight:237.299
Hs Code.:2924299090
DSSTox Substance ID:DTXSID70587631
Mol file:328956-56-5.mol

Synonyms:tert-butyl 2-(1-hydroxyethyl)phenylcarbamate

Suppliers and Price of tert-butyl N-[2-(1-hydroxyethyl)phenyl]carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
tert-Butyl(2-(1-hydroxyethyl)phenyl)carbamate 97%
1g
$ 490.00

American Custom Chemicals Corporation
1-(2-BOC-AMINO-PHENYL)-ETHANOL 95.00%
50MG
$ 717.21

Total 10 raw suppliers

Chemical Property of tert-butyl N-[2-(1-hydroxyethyl)phenyl]carbamate

Chemical Property:

Vapor Pressure:0.000192mmHg at 25°C
Boiling Point:314.8°C at 760 mmHg
PKA:13.78±0.70(Predicted)
Flash Point:144.2°C
PSA：58.56000
Density:1.132g/cm³
LogP:3.15990
XLogP3:2.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:237.13649347
Heavy Atom Count:17
Complexity:260

Purity/Quality:

97% ^*data from raw suppliers

tert-Butyl(2-(1-hydroxyethyl)phenyl)carbamate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C1=CC=CC=C1NC(=O)OC(C)(C)C)O

Technology Process of tert-butyl N-[2-(1-hydroxyethyl)phenyl]carbamate

There total 3 articles about tert-butyl N-[2-(1-hydroxyethyl)phenyl]carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 314773-77-8
tert-butyl (2-acetylphenyl)carbamate

: 328956-56-5
tert-butyl (2-(1-hydroxyethyl)phenyl)carbamate

Guidance literature:: With methanol; sodium tetrahydroborate; at 0 - 20 ℃; for 2h;
DOI:10.3390/molecules16098098

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 328956-56-5
tert-butyl (2-(1-hydroxyethyl)phenyl)carbamate

Guidance literature:: Multi-step reaction with 2 steps

1: dmap / tetrahydrofuran / 12 h / Reflux

2: methanol; sodium tetrahydroborate / 2 h / 0 - 20 °C

With methanol; dmap; sodium tetrahydroborate; In tetrahydrofuran;
DOI:10.3390/molecules16098098

Reference yield:

: 551-93-9
2-aminoacetophenone

: 328956-56-5
tert-butyl (2-(1-hydroxyethyl)phenyl)carbamate

Guidance literature:: Multi-step reaction with 2 steps

1: dmap / tetrahydrofuran / 12 h / Reflux

2: methanol; sodium tetrahydroborate / 2 h / 0 - 20 °C

With methanol; dmap; sodium tetrahydroborate; In tetrahydrofuran;
DOI:10.3390/molecules16098098