4-(5-amino-pyrimidin-2-ylamino)-N-(2-pyrrolidin-1-yl-ethyl)-benzenesulfonamide

Base Information

Chemical Name:4-(5-amino-pyrimidin-2-ylamino)-N-(2-pyrrolidin-1-yl-ethyl)-benzenesulfonamide
CAS No.:910903-73-0
Molecular Formula:C₁₆H₂₂N₆O₂S
Molecular Weight:362.456
Hs Code.:

Synonyms:4-(5-amino-pyrimidin-2-ylamino)-N-(2-pyrrolidin-1-yl-ethyl)-benzenesulfonamide

Suppliers and Price of 4-(5-amino-pyrimidin-2-ylamino)-N-(2-pyrrolidin-1-yl-ethyl)-benzenesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 4-(5-amino-pyrimidin-2-ylamino)-N-(2-pyrrolidin-1-yl-ethyl)-benzenesulfonamide

Chemical Property:

Purity/Quality:: 99% ，98% ^*data from raw suppliers

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Technology Process of 4-(5-amino-pyrimidin-2-ylamino)-N-(2-pyrrolidin-1-yl-ethyl)-benzenesulfonamide

There total 4 articles about 4-(5-amino-pyrimidin-2-ylamino)-N-(2-pyrrolidin-1-yl-ethyl)-benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 7.0%

: 910903-69-4
4-(5-nitro-pyrimidin-2-ylamino)-N-(2-pyrrolidin-1-yl-ethyl)-benzenesulfonamide

: 910903-73-0
4-(5-amino-pyrimidin-2-ylamino)-N-(2-pyrrolidin-1-yl-ethyl)-benzenesulfonamide

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In methanol; at 20 ℃; for 4h;

Reference yield:

: 7154-73-6
1-(2-aminoethyl)pyrrolidine

: 910903-73-0
4-(5-amino-pyrimidin-2-ylamino)-N-(2-pyrrolidin-1-yl-ethyl)-benzenesulfonamide

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / dichloromethane / 3 h

2: potassium tert-butylate / palladium diacetate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene / 1,4-dioxane / 18 h / 100 °C / Heating / reflux

3: hydrogen / palladium 10% on activated carbon / methanol / 4 h / 20 °C

With potassium tert-butylate; hydrogen; triethylamine; palladium diacetate; palladium 10% on activated carbon; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In 1,4-dioxane; methanol; dichloromethane;

Reference yield:

: 209968-27-4
4-bromo-N-(2-pyrrolidin-1-ylethyl)benzenesulfonamide

: 910903-73-0
4-(5-amino-pyrimidin-2-ylamino)-N-(2-pyrrolidin-1-yl-ethyl)-benzenesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: potassium tert-butylate / palladium diacetate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene / 1,4-dioxane / 18 h / 100 °C / Heating / reflux

2: hydrogen / palladium 10% on activated carbon / methanol / 4 h / 20 °C

With potassium tert-butylate; hydrogen; palladium diacetate; palladium 10% on activated carbon; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In 1,4-dioxane; methanol;