209968-27-4

Basic information

• Product Name: BenzenesulfonaMide, 4-broMo-N-[2-(1-pyrrolidinyl)ethyl]-
• Synonyms: BenzenesulfonaMide, 4-broMo-N-[2-(1-pyrrolidinyl)ethyl]-;4-Bromo-N-(2-(pyrrolidin-1-yl)ethyl)benzenesulfonamide
• CAS NO: 209968-27-4
• Molecular Formula: C₁₂H₁₇BrN₂O₂S
• Molecular Weight: 333.24458
• Mol File: 209968-27-4.mol

Chemical Properties

• Boiling Point: 437.4±55.0 °C(Predicted)
• Appearance: /
• Density: 1.458±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 9.38±0.50(Predicted)
• CAS DataBase Reference: BenzenesulfonaMide, 4-broMo-N-[2-(1-pyrrolidinyl)ethyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: BenzenesulfonaMide, 4-broMo-N-[2-(1-pyrrolidinyl)ethyl]-(209968-27-4)
• EPA Substance Registry System: BenzenesulfonaMide, 4-broMo-N-[2-(1-pyrrolidinyl)ethyl]-(209968-27-4)

Safety Data

• Hazardous Substances Data: 209968-27-4(Hazardous Substances Data)

Usage

Uses

Used in Medicinal Chemistry:
Benzenesulfonamide, 4-bromo-N-[2-(1-pyrrolidinyl)ethyl]is used as a chemical intermediate for the synthesis of various pharmaceuticals. Its unique structure allows it to be a versatile building block in the development of new drugs with potential therapeutic applications.
Used in Drug Development:
Benzenesulfonamide, 4-bromo-N-[2-(1-pyrrolidinyl)ethyl]is used as a lead compound in the discovery and optimization of new drugs. Its potential biological activity makes it a promising candidate for further research and development, with the aim of identifying novel therapeutic agents for various diseases and conditions.
Used in Chemical Synthesis:
Benzenesulfonamide, 4-bromo-N-[2-(1-pyrrolidinyl)ethyl]is used as a reactant in various chemical reactions, enabling the synthesis of a wide range of organic compounds. Its presence in these reactions can lead to the formation of new molecules with diverse properties and potential applications.
Used in Pharmaceutical Production:
Benzenesulfonamide, 4-bromo-N-[2-(1-pyrrolidinyl)ethyl]may be used in the production of pharmaceuticals, where it can contribute to the development of new drugs or the improvement of existing ones. Its presence in the manufacturing process can enhance the efficacy, safety, or stability of the final product.
Used as a Research Tool:
Benzenesulfonamide, 4-bromo-N-[2-(1-pyrrolidinyl)ethyl]can be used as a research tool in the study of biological processes and the development of novel therapeutic agents. Its unique structure and potential biological activity make it a valuable asset in the exploration of new scientific frontiers and the advancement of medical knowledge.

Upstream product

• 7154-73-6 1-(2-aminoethyl)pyrrolidine 
• 98-58-8 4-bromobenzenesulfonyl chloride 

Downstream Products

• 867331-34-8 4-bromo-N-isopropyl-N-(2-pyrrolidin-1-yl-ethyl)-benzenesulfonamide 
• 867332-75-0 4-bromo-N-ethyl-N-(2-pyrrolidin-1-yl-ethyl)-benzenesulfonamide 
• 910903-69-4 4-(5-nitro-pyrimidin-2-ylamino)-N-(2-pyrrolidin-1-yl-ethyl)-benzenesulfonamide 
• 910903-73-0 4-(5-amino-pyrimidin-2-ylamino)-N-(2-pyrrolidin-1-yl-ethyl)-benzenesulfonamide 
• 1142945-78-5 4-[4-(4-methyl-thiophen-2-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-ylamino]-N-(2-pyrrolidin-1-yl-ethyl)-benzenesulfonamide 
• 936092-33-0 4-(4-chloro-pyrimidin-2-ylamino)-N-(2-pyrrolidin-1-yl-ethyl)-benzenesulfonamide 
• 867333-00-4 4-[7-(3-benzyloxy-phenyl)-6-methoxy-1-oxy-benzo[1,2,4]triazin-3-ylamino]-N-(2-pyrrolidin-1-yl-ethyl)-benzenesulfonamide 
• 867331-00-8 4-[7-(2,6-dimethyl-phenyl)-5-nitro-1-oxy-benzo[1,2,4]triazin-3-ylamino]-N-(2-pyrrolidin-1-yl-ethyl)-benzenesulfonamide 

Relevant articles and documents

Substituted halogenated arylsulfonamides: A new class of σ receptor binding tumor imaging agents

The discovery of a series of novel halogenated arylsulfonamides (HAS) as new σ receptor binding tumor imaging agents is described. Several substituted halogenated sulfonamides have been prepared and characterized. Target compounds were examined for their

2-AMINO-5-SUBSTITUTED PYRIMIDINE INHIBITORS

Compounds having the general structure (A) are provided. The compounds of the invention are capable of inhibiting kinases, such as members of the Src kinase family, Vegfr and various other specific receptor and non-receptor kinases. Formula (I):

PYRIMIDINE COMPOUNDS AND METHODS OF USE

The invention provides pyrimidine compounds having formula (A): The pyrimidine compounds of the invention are capable of inhibiting kinases, such as members of the Src kinase family, and various other specific receptor and non-receptor kinases.