Ile-Phe

Base Information

Chemical Name:Ile-Phe
CAS No.:22951-98-0
Molecular Formula:C15H22 N2 O3
Molecular Weight:278.351
Hs Code.:2924299090
DSSTox Substance ID:DTXSID101309816
Nikkaji Number:J924.588J
Wikidata:Q27144388
Metabolomics Workbench ID:78849
ChEMBL ID:CHEMBL91330
Mol file:22951-98-0.mol

Synonyms:H-Ile-Phe-OH;22951-98-0;Ile-Phe;L-ISOLEUCYL-L-PHENYLALANINE;Isoleucyl-Phenylalanine;CHEMBL91330;CHEBI:74075;L-Ile-L-Phe;(S)-2-((2S,3S)-2-Amino-3-methylpentanamido)-3-phenylPropanoic acid;Ile-Phe-OH;L-Phenylalanine,L-isoleucyl-;SCHEMBL3512463;DTXSID101309816;BDBM50407438;MFCD00037253;AKOS010421266;Q27144388;(2S)-2-[[(2S,3S)-2-amino-3-methylpentanoyl]amino]-3-phenylpropanoic acid

Suppliers and Price of Ile-Phe

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
ILE-PHE-OH 98.00%
5G
$ 1674.75

Total 14 raw suppliers

Chemical Property of Ile-Phe

Chemical Property:

Boiling Point:501.2±50.0 °C(Predicted)
PKA:3.41±0.10(Predicted)
PSA：92.42000
Density:1.144±0.06 g/cm3(Predicted)
LogP:2.26310
Storage Temp.:-15°C
Solubility.:Methanol (Slightly, Sonicated)
XLogP3:-1.8
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:278.16304257
Heavy Atom Count:20
Complexity:327

Purity/Quality:

99% ^*data from raw suppliers

ILE-PHE-OH 98.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(C)C(C(=O)NC(CC1=CC=CC=C1)C(=O)O)N
Isomeric SMILES:CC[C@H](C)[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)O)N

Technology Process of Ile-Phe

There total 3 articles about Ile-Phe which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 85310-51-6
N-(benzyloxycarbonyl)isoleucylphenylalanine benzyl ester

: 22951-98-0
H-Ile-Phe-OH

Guidance literature:: With hydrogen; acetic acid; palladium; In methanol; Ambient temperature; overnight;
DOI:10.1246/bcsj.57.103

Reference yield:

: 35661-40-6
N-Fmoc L-Phe

: 71989-23-6,251316-98-0
Fmoc-Ile-OH

: 22951-98-0
H-Ile-Phe-OH

Guidance literature:: N-Fmoc L-Phe; With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 0.5h;

With N-ethyl-N,N-diisopropylamine; In methanol; dichloromethane;

Fmoc-Ile-OH; Further stages;
DOI:10.3390/md11124834