dithiocarbonic acid S-(1-{[acetyl(4-bromobenzenesulfonyl)amino]methyl}-4-oxo-4-piperidin-1-yl-butyl) ester O-ethyl ester

Base Information

• Chemical Name: dithiocarbonic acid S-(1-{[acetyl(4-bromobenzenesulfonyl)amino]methyl}-4-oxo-4-piperidin-1-yl-butyl) ester O-ethyl ester
• CAS No.: 851461-08-0
• Molecular Formula: C₂₁H₂₉BrN₂O₅S₃
• Molecular Weight: 565.574

Synonyms:dithiocarbonic acid S-(1-{[acetyl(4-bromobenzenesulfonyl)amino]methyl}-4-oxo-4-piperidin-1-yl-butyl) ester O-ethyl ester

Chemical Property of dithiocarbonic acid S-(1-{[acetyl(4-bromobenzenesulfonyl)amino]methyl}-4-oxo-4-piperidin-1-yl-butyl) ester O-ethyl ester

Chemical Property:

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of dithiocarbonic acid S-(1-{[acetyl(4-bromobenzenesulfonyl)amino]methyl}-4-oxo-4-piperidin-1-yl-butyl) ester O-ethyl ester

There total 3 articles about dithiocarbonic acid S-(1-{[acetyl(4-bromobenzenesulfonyl)amino]methyl}-4-oxo-4-piperidin-1-yl-butyl) ester O-ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

dithiocarbonic acid S-{1-[(4-bromobenzenesulfonylamino)methyl]-4-oxo-4-piperidin-1-yl-butyl} ester O-ethyl ester (851461-00-2) + acetyl chloride (75-36-5) → dithiocarbonic acid S-(1-{[acetyl(4-bromobenzenesulfonyl)amino]methyl}-4-oxo-4-piperidin-1-yl-butyl) ester O-ethyl ester (851461-08-0)

Guidance literature:

With dmap; In dichloromethane; at 20 ℃; for 2h;

DOI:10.1021/ol0503642

Reference yield:

N-allyl-4-bromobenzenesulfonamide (830-41-1) → dithiocarbonic acid S-(1-{[acetyl(4-bromobenzenesulfonyl)amino]methyl}-4-oxo-4-piperidin-1-yl-butyl) ester O-ethyl ester (851461-08-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 66 percent / lauroyl peroxide / 1,2-dichloro-ethane / Heating

2: 91 percent / DMAP / CH₂Cl₂ / 2 h / 20 °C

With dmap; dilauryl peroxide; In dichloromethane; 1,2-dichloro-ethane;

DOI:10.1021/ol0503642

Reference yield:

4-bromobenzenesulfonyl chloride (98-58-8) → dithiocarbonic acid S-(1-{[acetyl(4-bromobenzenesulfonyl)amino]methyl}-4-oxo-4-piperidin-1-yl-butyl) ester O-ethyl ester (851461-08-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 76 percent / NaOH / H₂O; diethyl ether / 5 h / 20 °C

2: 66 percent / lauroyl peroxide / 1,2-dichloro-ethane / Heating

3: 91 percent / DMAP / CH₂Cl₂ / 2 h / 20 °C

With dmap; sodium hydroxide; dilauryl peroxide; In diethyl ether; dichloromethane; water; 1,2-dichloro-ethane;

DOI:10.1021/ol0503642

upstream raw materials:

dithiocarbonic acid S-{1-[(4-bromobenzenesulfonylamino)methyl]-4-oxo-4-piperidin-1-yl-butyl} ester O-ethyl ester

acetyl chloride

N-allyl-4-bromobenzenesulfonamide

4-bromobenzenesulfonyl chloride

Downstream raw materials:

N-[2-(4-bromophenyl)-5-oxo-5-piperidin-1-yl-pentyl]acetamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 851461-08-0 dithiocarbonic acid S-(1-{[acetyl(4-bromobenzenesulfonyl)amino]methyl}-4-oxo-4-piperidin-1-yl-butyl) ester O-ethyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send