S-ethyl 2-(benzenesulfonamido)-3,4,6-tri-O-benzyl-2-deoxy-1-thio-β-D-glucopyranoside

Base Information

Chemical Name:S-ethyl 2-(benzenesulfonamido)-3,4,6-tri-O-benzyl-2-deoxy-1-thio-β-D-glucopyranoside
CAS No.:128358-56-5
Molecular Formula:C₃₅H₃₉NO₆S₂
Molecular Weight:633.83
Hs Code.:

Synonyms:S-ethyl 2-(benzenesulfonamido)-3,4,6-tri-O-benzyl-2-deoxy-1-thio-β-D-glucopyranoside

Suppliers and Price of S-ethyl 2-(benzenesulfonamido)-3,4,6-tri-O-benzyl-2-deoxy-1-thio-β-D-glucopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of S-ethyl 2-(benzenesulfonamido)-3,4,6-tri-O-benzyl-2-deoxy-1-thio-β-D-glucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of S-ethyl 2-(benzenesulfonamido)-3,4,6-tri-O-benzyl-2-deoxy-1-thio-β-D-glucopyranoside

There total 2 articles about S-ethyl 2-(benzenesulfonamido)-3,4,6-tri-O-benzyl-2-deoxy-1-thio-β-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 55628-54-1
3,4,6-tri-O-benzyl-D-glucal

: 128358-56-5
S-ethyl 2-(benzenesulfonamido)-3,4,6-tri-O-benzyl-2-deoxy-1-thio-β-D-glucopyranoside

Guidance literature:: Multi-step reaction with 2 steps

1: 78 percent / iodonium di-sym-collidine perchlorate, 4-A molecular sieves / CH₂Cl₂ / 0 °C

2: 1.) lithium hexamethyldisilazide / 1.) THF, DMF, -40 deg C, 2.) from -40 deg C to RT, 5 h

With iodonium(di-γ-collidine) perchlorate; 4 A molecular sieve; lithium hexamethyldisilazane; In dichloromethane;
DOI:10.1021/ja00171a021

Reference yield:

: 128358-45-2
N-(3,4,6-tri-O-benzyl-2-deoxy-2-iodo-α-D-mannopyranosyl)benzenesulfonamide

: 75-08-1
ethanethiol

: 128358-56-5
S-ethyl 2-(benzenesulfonamido)-3,4,6-tri-O-benzyl-2-deoxy-1-thio-β-D-glucopyranoside

Guidance literature:: With lithium hexamethyldisilazane; Yield given. Multistep reaction; 1.) THF, DMF, -40 deg C, 2.) from -40 deg C to RT, 5 h;
DOI:10.1021/ja00171a021

Reference yield: 67.0%

: 1198096-87-5
C₁₀₀H₉₈N₂O₂₀Si

: 128358-56-5
S-ethyl 2-(benzenesulfonamido)-3,4,6-tri-O-benzyl-2-deoxy-1-thio-β-D-glucopyranoside

: C₁₃₃H₁₃₁N₃O₂₆SSi

: C₁₃₃H₁₃₁N₃O₂₆SSi

Guidance literature:: C₁₀₀H₉₈N₂O₂₀Si; S-ethyl 2-(benzenesulfonamido)-3,4,6-tri-O-benzyl-2-deoxy-1-thio-β-D-glucopyranoside; With 2,6-di-tert-butyl-pyridine; In diethyl ether; dichloromethane; at 0 ℃; for 0.5h; Molecular sieve; Inert atmosphere;

With methyl trifluoromethanesulfonate; In diethyl ether; dichloromethane; at 0 ℃; for 2h; optical yield given as %de; Molecular sieve; Inert atmosphere;
DOI:10.1021/ja907136d