1-(4-CHLOROPHENYL)-2-HYDROXY-1-ETHANONE

Base Information

• Chemical Name: 1-(4-CHLOROPHENYL)-2-HYDROXY-1-ETHANONE
• CAS No.: 27993-56-2
• Molecular Formula: C8H7ClO2
• Molecular Weight: 170.595
• Hs Code.: 2914700090
• Mol file: 27993-56-2.mol

Synonyms:Acetophenone,4'-chloro-2-hydroxy- (8CI);1-(4-Chlorophenyl)-2-hydroxyethanone;2-Hydroxy-4'-chloroacetophenone;4-Chloro-a-hydroxyacetophenone;4'-Chloro-2-hydroxyacetophenone;4'-Chloro-a-hydroxyacetophenone;p-Chlorophenyl hydroxymethyl ketone;

Chemical Property of 1-(4-CHLOROPHENYL)-2-HYDROXY-1-ETHANONE

Chemical Property:

• Vapor Pressure: 0.000516mmHg at 25°C
• Melting Point: 127-129 °C
• Refractive Index: 1.568
• Boiling Point: 299.9 °C at 760 mmHg
• PKA: 12.63±0.10(Predicted)
• Flash Point: 135.2 °C
• PSA: 37.30000
• Density: 1.307 g/cm³
• LogP: 1.51500
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

1-(4-Chlorophenyl)-2-hydroxy-1-ethanone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(4-CHLOROPHENYL)-2-HYDROXY-1-ETHANONE

There total 39 articles about 1-(4-CHLOROPHENYL)-2-HYDROXY-1-ETHANONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

1-(p-chlorophenyl)ethyl alcohol (3391-10-4) + 3,3-dimethyldioxirane (74087-85-7) → para-chloroacetophenone (99-91-2) + 1-(4-chlorophenyl)-2-hydroxyethanone (27993-56-2)

Guidance literature:

In acetone; at 25 ℃; for 3h;

DOI:10.1016/S0040-4039(00)78488-7

Reference yield: 96.0%

1-(p-chlorophenyl)-1,2-ethanediol (7477-64-7) → 1-(4-chlorophenyl)-2-hydroxyethanone (27993-56-2)

Guidance literature:

With β‐cyclodextrin; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In water; acetone; at 20 ℃; for 12h;

DOI:10.1021/jo026751w

Reference yield: 96.0%

4-Chlorostyrene oxide (2788-86-5) → 1-(4-chlorophenyl)-2-hydroxyethanone (27993-56-2)

Guidance literature:

4-Chlorostyrene oxide; β‐cyclodextrin; In water; acetone; at 20 - 60 ℃;

With N-Bromosuccinimide; In water; acetone; at 20 ℃; for 24h;

DOI:10.1016/S0040-4039(02)00433-1

upstream raw materials:

2-Oxo-2-(4-chlorophenyl)ethyl formate

1-(4-chlorophenyl)-2-diazoethanone

((1-(4-chlorophenyl)vinyl)oxy)trimethylsilane

para-chloroacetophenone

Downstream raw materials:

1-(4-bromo-phenyl)-1-(4-chloro-phenyl)-ethane-1,2-diol

butyl-[4-(4-chloro-phenyl)-oxazol-2-yl]-amine

Methyl 4-chlorobenzoate

1-(4-Chloro-phenyl)-2-methoxymethoxy-ethanone

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 27993-56-2 1-(4-CHLOROPHENYL)-2-HYDROXY-1-ETHANONE

Send

Send

Metric Ton KG G Pound L ML

Send

Send