10-bromodecyl-tetra-O-benzoyl-β-D-glucopyranoside

Base Information

• Chemical Name: 10-bromodecyl-tetra-O-benzoyl-β-D-glucopyranoside
• CAS No.: 382607-66-1
• Molecular Formula: C₄₄H₄₇BrO₁₀
• Molecular Weight: 815.755
• Mol file: 382607-66-1.mol

Synonyms:10-bromodecyl-tetra-O-benzoyl-β-D-glucopyranoside

Chemical Property of 10-bromodecyl-tetra-O-benzoyl-β-D-glucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of 10-bromodecyl-tetra-O-benzoyl-β-D-glucopyranoside

There total 5 articles about 10-bromodecyl-tetra-O-benzoyl-β-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

β-1-bromo-2,3,4,6-tetra-O-benzoyl-α-D-glucopyranoside (114682-36-9,14218-11-2,14218-30-5,61198-88-7,108438-33-1,108836-02-8,127305-34-4,151377-77-4) + 1-bromo-10-decanol (53463-68-6) → 10-bromodecyl-tetra-O-benzoyl-β-D-glucopyranoside (382607-66-1)

Guidance literature:

With silver orthophosphate; 3 A molecular sieve; In nitromethane;

DOI:10.1021/jm010006e

Reference yield:

2,3,4,6-tetra-O-benzoyl-α-D-glucopyranosyl iodide (14262-85-2,14726-07-9) + 1-bromo-10-decanol (53463-68-6) → 10-bromodecyl-tetra-O-benzoyl-β-D-glucopyranoside (382607-66-1)

Guidance literature:

With zinc(II) chloride; In dichloromethane; for 17h; Inert atmosphere; Molecular sieve;

Reference yield:

benzoyl chloride (98-88-4) → 10-bromodecyl-tetra-O-benzoyl-β-D-glucopyranoside (382607-66-1)

Guidance literature:

Multi-step reaction with 3 steps

1: pyridine / 2.17 h / 0 - 20 °C

2: 1,1,1,2,2,2-hexamethyldisilane; zinc(II) iodide; iodine / dichloromethane / 16 h

3: zinc(II) chloride / dichloromethane / 17 h / Inert atmosphere; Molecular sieve

With pyridine; 1,1,1,2,2,2-hexamethyldisilane; iodine; zinc(II) iodide; zinc(II) chloride; In dichloromethane;

upstream raw materials:

β-1-bromo-2,3,4,6-tetra-O-benzoyl-α-D-glucopyranoside

1-bromo-10-decanol

2,3,4,6-tetra-O-benzoyl-α-D-glucopyranosyl iodide

1,2,3,4,6-penta-O-benzoyl-α-D-glucopyranose

Downstream raw materials:

10-[O⁶-(4-bromothenyl)-guan-9-yl]-decyl-β-D-tetra-O-benzoylglucoside