1-BROMOHEXADECANE-D33

Base Information

• Chemical Name: 1-BROMOHEXADECANE-D33
• CAS No.: 284474-41-5
• Molecular Formula: C₁₆H₃₃Br
• Molecular Weight: 338.08
• Mol file: 284474-41-5.mol

Synonyms:HEXADECYL BROMIDE-D33;CETYL BROMIDE-D33;1-BROMOHEXADECANE-D33;Cetyl bromide-d33, Hexadecyl bromide-d33

Chemical Property of 1-BROMOHEXADECANE-D33

Chemical Property:

• Melting Point: 16-18 °C(lit.)
• Boiling Point: 190 °C11 mm Hg(lit.)
• Flash Point: 177 °C
• PSA: 0.00000
• Density: 1.105 g/mL at 25 °C
• LogP: 6.86260

Purity/Quality:

99% by CP; 98% atom D ^*data from raw suppliers

1-Bromohexadecane-d33 98 atom % D ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 1-Bromohexadecane-D33 is a useful isotopically labeled research compound used in the preparation of lipophilic nucleosides via esterification, amidation and alkylation from uridine derivatives.

Technology Process of 1-BROMOHEXADECANE-D33

There total 2 articles about 1-BROMOHEXADECANE-D33 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

1-hexadecyl-d33-ol (284474-73-3,1219799-18-4,1219799-21-9) → [D33]-hexadecyl bromide (284474-41-5,1219805-65-8,284474-40-4)

Guidance literature:

With hydrogen bromide; Heating;

DOI:10.1021/jp031273u

Reference yield:

palmitic acid-d31 (39756-30-4,272442-14-5,285979-77-3,358730-99-1,78387-70-9,1219802-61-5) → [D33]-hexadecyl bromide (284474-41-5,1219805-65-8,284474-40-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 98 percent / LiAlD₄ / tetrahydrofuran

2: 83 percent / aq. HBr / Heating

With lithium aluminium deuteride; hydrogen bromide; In tetrahydrofuran;

DOI:10.1021/jp031273u

Reference yield: 94.0%

[D33]-hexadecyl bromide (284474-41-5,1219805-65-8,284474-40-4) → d33-hexadecanethiol (218956-22-0)

Guidance literature:

[D₃₃]-hexadecyl bromide; With sodium thiosulfate; In ethanol; Heating;

With hydrogenchloride;

DOI:10.1021/jp031273u

upstream raw materials:

1-hexadecyl-d33-ol

palmitic acid-d31

Downstream raw materials:

C₁₉⁽²⁾H₄₂N⁽¹⁺⁾*Br^(1-)

d33-hexadecanethiol