PENTANEDIOIC-2,2,4,4-D4 ACID

Base Information

• Chemical Name: PENTANEDIOIC-2,2,4,4-D4 ACID
• CAS No.: 19136-99-3
• Molecular Formula: C₅H₈O₄
• Molecular Weight: 136.084
• Mol file: 19136-99-3.mol

Synonyms:Glutaric-2,2,4,4-d4acid (8CI)

Chemical Property of PENTANEDIOIC-2,2,4,4-D4 ACID

Chemical Property:

• PSA: 74.60000
• LogP: 0.32590
• Storage Temp.: Refrigerator
• Solubility.: DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

Glutaric-d4Acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of PENTANEDIOIC-2,2,4,4-D4 ACID

There total 4 articles about PENTANEDIOIC-2,2,4,4-D4 ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

Dimethyl-α,α,α',α'-Tetradeuterioglutarat (14130-70-2) → 2,2,4,4-tetradeuterio-pentanedioic acid (19136-99-3)

Guidance literature:

With diclazuril; water-d2; for 16h; Heating;

DOI:10.1002/hlca.19970800410

Reference yield: 70.0%

1,5-pentanedioic acid (110-94-1) → 2,2,4,4-tetradeuterio-pentanedioic acid (19136-99-3)

Guidance literature:

With sodium hydroxide; water-d2; at 150 ℃; for 24h;

DOI:10.1021/ja00291a007

Reference yield:

Dimethyl glutarate (1119-40-0) → 2,2,4,4-tetradeuterio-pentanedioic acid (19136-99-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 99 percent / MeONa, MeOD / 72 h / Heating

2: 99 percent / DCl, D₂O / 16 h / Heating

With diclazuril; deuteromethanol; water-d2; sodium methylate;

DOI:10.1002/hlca.19970800410

upstream raw materials:

1,5-pentanedioic acid

Dimethyl-α,α,α',α'-Tetradeuterioglutarat

Dimethyl glutarate

Downstream raw materials:

C₅H₂⁽²⁾H₈Br₂

Refernces

• 1、 Lompa Krzymien,Leitch. "Synthesis of some symmetrically deuterated cyclohexanones". . p. 331 - 338. Retrieved 2007/10/12.