N-(4-Methoxy-phenyl)-N-(2-nitro-benzyl)-oxalamic acid ethyl ester

Base Information

• Chemical Name: N-(4-Methoxy-phenyl)-N-(2-nitro-benzyl)-oxalamic acid ethyl ester
• CAS No.: 151383-64-1
• Molecular Formula: C₁₈H₁₈N₂O₆
• Molecular Weight: 358.351
• Mol file: 151383-64-1.mol

Synonyms:N-(4-Methoxy-phenyl)-N-(2-nitro-benzyl)-oxalamic acid ethyl ester

Chemical Property of N-(4-Methoxy-phenyl)-N-(2-nitro-benzyl)-oxalamic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(4-Methoxy-phenyl)-N-(2-nitro-benzyl)-oxalamic acid ethyl ester

There total 1 articles about N-(4-Methoxy-phenyl)-N-(2-nitro-benzyl)-oxalamic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

4-methoxy-N-(2-nitrobenzyl)benzenamine (151383-59-4) + Ethyl oxalyl chloride (4755-77-5) → N-(4-Methoxy-phenyl)-N-(2-nitro-benzyl)-oxalamic acid ethyl ester (151383-64-1)

Guidance literature:

With pyridine; In benzene; for 0.166667h;

Reference yield: 64.0%

N-(4-Methoxy-phenyl)-N-(2-nitro-benzyl)-oxalamic acid ethyl ester (151383-64-1) → 5-Methoxy-1-(2-nitro-benzyl)-1H-indole-2,3-dione (151383-70-9)

Guidance literature:

With phosphorus pentachloride; In tetrachloromethane; for 12h; Ambient temperature;

Reference yield:

N-(4-Methoxy-phenyl)-N-(2-nitro-benzyl)-oxalamic acid ethyl ester (151383-64-1) → 8-hydroxy-indolo<2,1-b>quinazolin-6(12H)-one

Guidance literature:

Multi-step reaction with 3 steps

1: 64 percent / PCl₅ / CCl₄ / 12 h / Ambient temperature

2: 33 percent / stannous chloride dihydrate, conc. HCl / ethanol / 0.5 h / 60 °C

3: 42 percent / 48percent HBr / 2 h / Heating

With hydrogenchloride; phosphorus pentachloride; hydrogen bromide; tin(ll) chloride; In tetrachloromethane; ethanol;

upstream raw materials:

4-methoxy-N-(2-nitrobenzyl)benzenamine

Ethyl oxalyl chloride

Downstream raw materials:

5-Methoxy-1-(2-nitro-benzyl)-1H-indole-2,3-dione