Cyclopropane-1,1-d2

Base Information

• Chemical Name: Cyclopropane-1,1-d2
• CAS No.: 65146-94-3
• Molecular Formula: C₃H₆
• Molecular Weight: 44.0648
• Mol file: 65146-94-3.mol

Synonyms:1,1-Dideuteriocyclopropane;1,1-Dideuterocyclopropane

Chemical Property of Cyclopropane-1,1-d2

Chemical Property:

• PSA: 0.00000
• LogP: 1.17030

Purity/Quality:

98% ^*data from raw suppliers

Cyclopropane-1,1-d2gas ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Cyclopropane-1,1-d2

There total 14 articles about Cyclopropane-1,1-d2 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,1-dibromocyclopropane (3591-34-2) → cyclopropane-1,1-d2 (65146-94-3)

Guidance literature:

With 2,2'-azobis(isobutyronitrile); tributyltin deuteride; In benzene; at 60 ℃; for 24h;

DOI:10.1021/ja000112q

Reference yield:

3-(dimethylphenylsilyl)[1,1-2H2]propyl tosylate (261381-49-1) → cyclopropane-1,1-d2 (65146-94-3) + 3-(dimethylphenylsilyl)-1-[1,1-2H2]propanol (261381-46-8)

Guidance literature:

With water; In 2,2,2-trifluoroethanol; at 75 ℃; Kinetics;

DOI:10.1246/bcsj.73.429

Reference yield:

3-[p-methoxyphenyl(dimethyl)silyl][1,1-2H2]propyl tosylate (261381-50-4) → cyclopropane-1,1-d2 (65146-94-3) + 3-[p-methoxyphenyl(dimethyl)silyl]-1-[1,1-2H2]propanol (261381-47-9)

Guidance literature:

With water; In 2,2,2-trifluoroethanol; at 75 ℃; Kinetics;

DOI:10.1246/bcsj.73.429

upstream raw materials:

ethanol

3-(dimethylphenylsilyl)[1,1-2H₂]propyl tosylate

3-[p-methoxyphenyl(dimethyl)silyl][1,1-2H₂]propyl tosylate

3-[dimethyl(m-trifluoromethylphenyl)silyl][1,1-2H₂]propyl tosylate

Refernces

• 1、 Fujio, Mizue,Nakashima, Tohru,Fujiyama, Ryoji,Kim, Hyun-Joong,Tsuno, Yuho. "The γ-silicon effect on solvolyses of the 3-(aryldimethylsilyl)propyl system". . p. 612 - 615. Retrieved 2007/10/03.
• 2、 Baldwin, John E.,Patel, Dharmesh B.. "Cyclobutanone-3,3-d2 and trimethylene-2,2-d2". . p. 55 - 61. Retrieved 2007/10/03.