C₉H₈ClNO₃

Base Information

• Chemical Name: C₉H₈ClNO₃
• CAS No.: 1269219-36-4
• Molecular Formula: C₉H₈ClNO₃
• Molecular Weight: 213.62
• Mol file: 1269219-36-4.mol

Synonyms:C₉H₈ClNO₃

Chemical Property of C₉H₈ClNO₃

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of C₉H₈ClNO₃

There total 1 articles about C₉H₈ClNO₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 1-chloro-4-(2-nitrovinyl)benzene (706-07-0,5153-70-8) → C9H8ClNO3 (1269219-36-4)

Guidance literature:

With 1H-imidazole; In tetrahydrofuran; water; at 20 ℃; for 72h;

DOI:10.1039/c7nj03292g

Reference yield: 93.0%

C9H8ClNO3 (1269219-36-4) → 2-(4-chlorophenyl)-3-nitrothietane

Guidance literature:

With sodium O,O-diethyl phosphorodithioate; In tetrahydrofuran; mineral oil; at 20 ℃; for 4h; diastereoselective reaction; Inert atmosphere;

DOI:10.1016/j.tet.2012.01.062

Reference yield: 92.0%

C9H8ClNO3 (1269219-36-4) + diethyl phenylphosphoramidate (1445-38-1) → C15H13ClN2O2

Guidance literature:

diethyl phenylphosphoramidate; With sodium hydride; In tetrahydrofuran; at 60 ℃; for 0.5h; Inert atmosphere;

C₉H₈ClNO₃; In tetrahydrofuran; at 20 ℃; for 3.5h; diastereoselective reaction; Inert atmosphere;

DOI:10.1039/c1ob06274c

upstream raw materials:

formaldehyd

1-chloro-4-(2-nitrovinyl)benzene

Downstream raw materials:

(2R,4R,5R)-4-(4-chlorophenyl)-2-methyl-5-nitrotetrahydro-2H-pyran-2-ol

C₉H₆ClNO₃