1-(2,4-dihydroxy-6-((3-methylbut-2-en-1-yl)oxy)phenyl)ethan-1-one

Base Information

• Chemical Name: 1-(2,4-dihydroxy-6-((3-methylbut-2-en-1-yl)oxy)phenyl)ethan-1-one
• CAS No.: 1246764-81-7
• Molecular Formula: C₁₃H₁₆O₄
• Molecular Weight: 236.268
• Mol file: 1246764-81-7.mol

Synonyms:1-(2,4-dihydroxy-6-((3-methylbut-2-en-1-yl)oxy)phenyl)ethan-1-one

Chemical Property of 1-(2,4-dihydroxy-6-((3-methylbut-2-en-1-yl)oxy)phenyl)ethan-1-one

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 1-(2,4-dihydroxy-6-((3-methylbut-2-en-1-yl)oxy)phenyl)ethan-1-one

There total 3 articles about 1-(2,4-dihydroxy-6-((3-methylbut-2-en-1-yl)oxy)phenyl)ethan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 28.0%

2,4,6-trihydroxyacetophenone (480-66-0,67471-34-5) + prenyl bromide (870-63-3) → 1-(2,6-dihydroxy-4-((3-methylbut-2-en-1-yl)oxy)phenyl)ethan-1-one (1246764-80-6) + 1-(2,4-dihydroxy-6-((3-methylbut-2-en-1-yl)oxy)phenyl)ethan-1-one (1246764-81-7)

Guidance literature:

With potassium carbonate; In acetone; at 60 ℃; for 16h; regioselective reaction; Inert atmosphere;

DOI:10.1039/d1ob02228h

Reference yield: 6.0%

2,4,6-trihydroxyacetophenone (480-66-0,67471-34-5) + prenyl bromide (870-63-3) → 2',4',6'-trihydroxy-3'-(3-methyl-2-butenyl)acetophenone (27364-71-2) + 1-[2,4,6-trihydroxy-3,5-di(3-methyl-2-buten-1-yl)phenyl]ethanone (35458-19-6) + 1-(2,6-dihydroxy-4-((3-methylbut-2-en-1-yl)oxy)phenyl)ethan-1-one (1246764-80-6) + 1-(2,4-dihydroxy-6-((3-methylbut-2-en-1-yl)oxy)phenyl)ethan-1-one (1246764-81-7)

Guidance literature:

With potassium carbonate; In acetone; at 74 ℃; for 4h;

DOI:10.1016/j.ejmech.2010.06.025

Reference yield:

2,4,6-trihydroxyacetophenone (480-66-0,67471-34-5) + prenyl bromide (870-63-3) → 2',4',6'-trihydroxy-3'-(3-methyl-2-butenyl)acetophenone (27364-71-2) + 1-(2,6-dihydroxy-4-((3-methylbut-2-en-1-yl)oxy)phenyl)ethan-1-one (1246764-80-6) + 1-(2,4-dihydroxy-6-((3-methylbut-2-en-1-yl)oxy)phenyl)ethan-1-one (1246764-81-7)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 50 ℃; for 8h; Reagent/catalyst; Inert atmosphere;

DOI:10.1039/d1ob02228h

upstream raw materials:

2,4,6-trihydroxyacetophenone

prenyl bromide