35458-19-6

Upstream product

• 480-66-0 2,4,6-trihydroxyacetophenone 
• 870-63-3 prenyl bromide 
• 108-73-6 3,5-dihydroxyphenol 
• 20038-12-4 4-bromo-2-methylbut-1-ene 

Downstream Products

• 119415-25-7 1-[2,4-bis-benzoyloxy-6-hydroxy-3,5-bis-(3-methyl-but-2-enyl)-phenyl]-ethanone 
• 122541-79-1 1-[2,4,6-tris-benzoyloxy-3,5-bis-(3-methyl-but-2-enyl)-phenyl]-ethanone 
• 130236-66-7 4,6-bis-ethoxymethoxy-2-hydroxy-3,5-di-C-prenylacetophenone 
• 131303-37-2 2-hydroxy-3,5-bis(3-methyl-2-butenyl)-4,6-dimethoxymethoxyacetophenone 
• 55380-57-9 1-[2,4,6-Trihydroxy-3,5-bis-(3-methyl-butyl)-phenyl]-ethanone 
• 212265-21-9 6,8-bis(3-methyl-2-butenyl)-5,7,2',4',6'-pentamethoxymethoxyflavanone 
• 130322-09-7 euchrenone a3 
• 130236-69-0 4',6'-bisethoxymethoxy-2'-hydroxy-6'',6''-dimethyl-3',5'-di-C-prenylpyrano<2'',3'',4,3>chalcone 
• 130236-68-9 amorilin 4',5,7-trisethoxymethyl ether 
• 130236-67-8 4,4',6'-trisethoxymethoxy-2'-hydroxy-3,3',5'-tri-C-prenylchalcone 

Relevant academic research and scientific papers

Total Synthesis and in Vitro Anti-Tumor-Promoting Activities of Racemic Acetophenone Monomers from Acronychia trifoliolata

Six acetophenone derivatives, acronyculatins I (1), J (2), K (3), L (4), N (5), and O (6), were recently isolated from Acronychia trifoliolata, and the structure of the known acronyculatin B (7) was revised. Because of the limited quantities of isolated p

BENZOPYRONE ESTROGEN RECEPTOR REGULATOR

The present invention provides a kind of benzopyrone compounds having a structure of formula (I) and the pharmaceutically acceptable salts or prodrugs thereof, and the pharmaceutical compositions containing such compounds, which can be used to regulate the novel estrogen receptor ER-a36, and prevent and/or treat the related diseases mediated by the ER-a36 receptor, such as cancers, etc.

BENZOPYRONE ESTROGEN RECEPTOR REGULATOR

The present invention provides a kind of benzopyrone compounds having a structure of formula (I) and the pharmaceutically acceptable salts or prodrugs thereof, and the pharmaceutical compositions containing such compounds, which can be used to regulate the novel estrogen receptor ER-a36, and prevent and/or treat the related diseases mediated by the ER-a36 receptor, such as cancers, etc.

Prenylflavonoids and prenyl/alkyl-phloroacetophenones: Synthesis and antitumour biological evaluation

Several prenylflavonoids have been synthesised and tested against human tumour cell lines. The prenyl unit has been geranyl or a labdane diterpene. These labdane-flavonoids have been synthesised for the first time. The antitumour activity increase with the prenylation at C-8 position. Twenty-three C and O-prenylated acylphloroglucinols have been synthesised as well. In this case the C-alkylation products have resulted, in general, more active.

First total synthesis of (±)-kenusanone b

The first total synthesis of a natural prenylflavanone, (±)-kenusanone B (1) has been achieved by condensation of acetophenone 4 and benzaldehyde 6 followed by cyclization and deprotection. Chloromethyl methyl ether was used as a facile protecting reagent of free hydroxy groups for the synthesis of polyhydroxylated flavanones.