Technology Process of 2-<2-(hydroxymethyl)benzyl>-1,4-dimethoxy-5.6-dimethylbenzene
There total 5 articles about 2-<2-(hydroxymethyl)benzyl>-1,4-dimethoxy-5.6-dimethylbenzene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
1.) RT, 2.) reflux, 6h;
DOI:10.1021/jo00226a034
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 82 percent / trifluoroacetic anhydride / 22 h / Heating
2: 87 percent / sodium hydroxide, zinc, cupric sulfate / H2O / 18 h / Heating
3: 74 percent / hydrogen, 70percent perchloric acid / palladium on carbon / ethyl acetate; acetic acid / 25 h / 760 Torr
4: 86 percent / LiAlH4 / tetrahydrofuran / 1.) RT, 2.) reflux, 6h
With
sodium hydroxide; lithium aluminium tetrahydride; perchloric acid; hydrogen; copper(II) sulfate; trifluoroacetic anhydride; zinc;
palladium on activated charcoal;
In
tetrahydrofuran; water; acetic acid; ethyl acetate;
DOI:10.1021/jo00226a034
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 82 percent / trifluoroacetic anhydride / 22 h / Heating
2: 87 percent / sodium hydroxide, zinc, cupric sulfate / H2O / 18 h / Heating
3: 74 percent / hydrogen, 70percent perchloric acid / palladium on carbon / ethyl acetate; acetic acid / 25 h / 760 Torr
4: 86 percent / LiAlH4 / tetrahydrofuran / 1.) RT, 2.) reflux, 6h
With
sodium hydroxide; lithium aluminium tetrahydride; perchloric acid; hydrogen; copper(II) sulfate; trifluoroacetic anhydride; zinc;
palladium on activated charcoal;
In
tetrahydrofuran; water; acetic acid; ethyl acetate;
DOI:10.1021/jo00226a034
