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1,4-DiMethoxy-2,3-diMethylbenzene is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 39021-83-5 Structure
  • Basic information

    1. Product Name: 1,4-DiMethoxy-2,3-diMethylbenzene
    2. Synonyms: 1,4-DiMethoxy-2,3-diMethylbenzene
    3. CAS NO:39021-83-5
    4. Molecular Formula: C10H14O2
    5. Molecular Weight: 166.21696
    6. EINECS: -0
    7. Product Categories: N/A
    8. Mol File: 39021-83-5.mol
  • Chemical Properties

    1. Melting Point: 78 °C
    2. Boiling Point: 246.5°C at 760 mmHg
    3. Flash Point: 92.4°C
    4. Appearance: /
    5. Density: 0.977g/cm3
    6. Vapor Pressure: 0.0425mmHg at 25°C
    7. Refractive Index: 1.491
    8. Storage Temp.: Sealed in dry,Room Temperature
    9. Solubility: N/A
    10. CAS DataBase Reference: 1,4-DiMethoxy-2,3-diMethylbenzene(CAS DataBase Reference)
    11. NIST Chemistry Reference: 1,4-DiMethoxy-2,3-diMethylbenzene(39021-83-5)
    12. EPA Substance Registry System: 1,4-DiMethoxy-2,3-diMethylbenzene(39021-83-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 39021-83-5(Hazardous Substances Data)

39021-83-5 Usage

Synthesis Reference(s)

Journal of the American Chemical Society, 64, p. 528, 1942 DOI: 10.1021/ja01255a016

Check Digit Verification of cas no

The CAS Registry Mumber 39021-83-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,9,0,2 and 1 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 39021-83:
(7*3)+(6*9)+(5*0)+(4*2)+(3*1)+(2*8)+(1*3)=105
105 % 10 = 5
So 39021-83-5 is a valid CAS Registry Number.
InChI:InChI=1/C10H14O2/c1-7-8(2)10(12-4)6-5-9(7)11-3/h5-6H,1-4H3

39021-83-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 1,4-Dimethoxy-2,3-dimethylbenzene

1.2 Other means of identification

Product number -
Other names 2,3-dimethyl-1,4-dimethoxybenzene

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:39021-83-5 SDS

39021-83-5Relevant articles and documents

Understanding the binding properties of phosphorylated glycoluril-derived molecular tweezers and selective nanomolar binding of natural polyamines in aqueous solution

Heilmann, Michael,Knezevic, Melina,Piccini, Giovannimaria,Tiefenbacher, Konrad

supporting information, p. 3628 - 3633 (2021/05/04)

A modular synthetic platform for the construction of flexible glycoluril-derived molecular tweezers was developed. The binding properties of four exemplary supramolecular hosts obtained via this approach towards 16 organic amines were investigated by means of 1H NMR titration. In this work, we compare the Ka values obtained this way with those of three structurally related molecular tweezers and provide a computational approach towards an explanation of the observed behavior of those novel hosts. The results showcase that certain structural modifications lead to very potent and selective binders of natural polyamines, with observed binding of spermine below 10 nM. This journal is

Overriding Intrinsic Reactivity in Aliphatic C?H Oxidation: Preferential C3/C4 Oxidation of Aliphatic Ammonium Substrates

Heilmann, Michael,Knezevic, Melina,Piccini, Giovanni Maria,Tiefenbacher, Konrad

supporting information, p. 12387 - 12391 (2020/07/04)

The site-selective C?H oxidation of unactivated positions in aliphatic ammonium chains poses a tremendous synthetic challenge, for which a solution has not yet been found. Here, we report the preferential oxidation of the strongly deactivated C3/C4 positions of aliphatic ammonium substrates by employing a novel supramolecular catalyst. This chimeric catalyst was synthesized by linking the well-explored catalytic moiety Fe(pdp) to an alkyl ammonium binding molecular tweezer. The results highlight the vast potential of overriding the intrinsic reactivity in chemical reactions by guiding catalysis using supramolecular host structures that enable a precise orientation of the substrates.

PREPARATION AND USES OF REACTIVE OXYGEN SPECIES SCAVENGER DERIVATIVES

-

Page/Page column 93-94, (2019/03/07)

Compounds of Formula (I) a or (I) b: including certain quinone derivatives, and the corresponding pharmaceutical compositions, which may serve to modulate ferroptosis in a subject. Also disclosed herein are the preparations of these compounds and pharmaceutical compositions and their potential uses in the manufacture of a medicament in reducing reactive oxygen species (ROS) in a cell and for preventing, treating, ameliorating certain related disorder or a disease.

Regioselective bromination of 1,4-dimethoxy-2,3-dimethylbenzene and conversion into sulfur-functionalised benzoquinones

Aitken, R. Alan,Jethwa, Siddharth J.,Richardson, Neville V.,Slawin, Alexandra M.Z.

supporting information, p. 1563 - 1566 (2018/03/29)

The NBS bromination of 1,4-dimethoxy-2,3-dimethylbenzene has been examined under a variety of conditions in both 1,1,1-trichloroethane and benzotrifluoride. Four different bromination products have been isolated including the previously unknown 1-bromo-4-

Microwave-assisted methylation of dihydroxybenzene derivatives with dimethyl carbonate

Lui, Matthew Y.,Lokare, Kapil S.,Hemming, Ellen,Stanley, Jessica N.G.,Perosa, Alvise,Selva, Maurizio,Masters, Anthony F.,Maschmeyer, Thomas

, p. 58443 - 58451 (2016/07/06)

Using a focused microwave reactor, methylation with dimethyl carbonate (DMC) of 1,2- and 1,4-dihydroxybenzene derivatives, found in the product spectrum of lignin depolymerisation, leads to the respective aromatic bis-methyl ethers with excellent isolated yields. Stoichiometric as well as catalytic amounts of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) are effective for the bis-methylation of these dihydroxybenzenes at relatively mild temperatures (160-190 °C). Conversion of resorcinol (1,3-dihydroxybenzene) under similar conditions leads to a mixture of 1,3-dimethoxybenzene and methyl 2,4-dimethoxybenzoate. The unusual reactivity of resorcinol's phenyl ring towards DMC can be explained by the synergic effect of its two strongly activating ortho/para directing groups.

Rh-Catalyzed Reactions of 1,4-Benzoquinones with Electrophiles: C-H Iodination, Bromination, and Phenylselenation

Jardim, Guilherme A. M.,Bower, John F.,Da Silva Júnior, Eufranio N.

supporting information, p. 4454 - 4457 (2016/09/28)

Under Rh-catalyzed conditions, typically electrophilic 1,4-benzoquinones exhibit nucleophilic reactivity, such that exposure to appropriate electrophiles generates products of C-H iodination, bromination, and phenylselenation. This provides a mild and general method for direct halofunctionalization, and the first method that can achieve direct C-H phenylselenation of this compound class. The scope and limitations of the new protocols are outlined, and representative derivatizations are highlighted.

ALKYLATION OF PHENOLIC COMPOUNDS

-

Page/Page column 36, (2015/04/28)

The invention relates to a process for O-alkyiation of a phenolic compound comprising at least two hydroxyl groups bonded to an aromatic hydrocarbon, the process comprising reacting the phenolic compound with an alkylating agent in the presence of a base, at a suitable reaction temperature and for a suitable time period, thereby alkylating the at least two hydroxy] groups. The invention also relates to O-alkylaled phenolic compounds produced by this process.

PYRAZOLOPYRIDINE PYRAZOLOPYRIMIDINE AND RELATED COMPOUNDS

-

Paragraph 0505; 0506, (2015/11/25)

In one aspect this invention relates generally to compounds of Formula: and sub-formulas thereof, or a tautomer of each thereof, a pharmaceutically acceptable salt of each thereof, or a pharmaceutically acceptable solvate of each of the foregoing, where X1, L1, L3, and R3 are described herein.

Total synthesis of (R, R, R)-γ-tocopherol through cu-catalyzed asymmetric 1,2-addition

Wu, Zhongtao,Harutyunyan, Syuzanna R.,Minnaard, Adriaan J.

supporting information, p. 14250 - 14255 (2015/03/18)

Based on the asymmetric copper-catalyzed 1,2-addition of Grignard reagents to ketones, (R, R, R)-γ-tocopherol has been synthesized in 36% yield over 12 steps (longest linear sequence). The chiral center in the chroman ring was constructed with 73% ee by the 1,2-addition of a phytol-derived Grignard reagent to an a-bromo enone prepared from 2,3-dimethylquinone.

Composition for treatment of pathogens that are resistant to tetracyclines

-

Paragraph 0103-0104, (2014/08/19)

The invention relates to compounds and pharmaceutical compositions useful in combination with tetracyclines in the treatment of bacterial infections caused by Gram-positive and Gram-negative pathogens, with particular efficacy in tetracycline resistant st

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