(3R,4R)-1-benzylpyrrolidine-3,4-diamine

Base Information

Chemical Name:(3R,4R)-1-benzylpyrrolidine-3,4-diamine
CAS No.:140134-21-0
Molecular Formula:C11H17 N3
Molecular Weight:191.276
Hs Code.:
European Community (EC) Number:691-491-6
DSSTox Substance ID:DTXSID00466607
Nikkaji Number:J860.400B
Wikidata:Q76421544
Mol file:140134-21-0.mol

Synonyms:140134-21-0;(3R,4R)-1-benzylpyrrolidine-3,4-diamine;(3R,4R)-(-)-3,4-Diamino-1-benzylpyrrolidine;(R,R)-N-Benzyl-3,4-trans-diaminopyrrolidine;SCHEMBL5836807;DTXSID00466607;AKOS006284311;AKOS015854200;D4035;(3R,4R)-(-)-1-Benzyl-3,4-pyrrolidinediamine;(3R,4R)-3,4-Diamino-1-benzylpyrrolidine, >=85.0% (HPLC)

Suppliers and Price of (3R,4R)-1-benzylpyrrolidine-3,4-diamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(R,R)-N-Benzyl-3,4-trans-diaminopyrrolidine
2mg
$ 65.00

Biosynth Carbosynth
(3R,4R)-(-)-3,4-Diamino-1-benzylpyrrolidine
250 mg
$ 378.00

Biosynth Carbosynth
(3R,4R)-(-)-3,4-Diamino-1-benzylpyrrolidine
100 mg
$ 189.00

Biosynth Carbosynth
(3R,4R)-(-)-3,4-Diamino-1-benzylpyrrolidine
50 mg
$ 111.00

Biosynth Carbosynth
(3R,4R)-(-)-3,4-Diamino-1-benzylpyrrolidine
25 mg
$ 64.00

Biosynth Carbosynth
(3R,4R)-(-)-3,4-Diamino-1-benzylpyrrolidine
500 mg
$ 643.00

American Custom Chemicals Corporation
(R,R)-N-BENZYL-3,4-TRANS-DIAMINOPYRROLIDINE 95.00%
5MG
$ 504.32

Total 8 raw suppliers

Chemical Property of (3R,4R)-1-benzylpyrrolidine-3,4-diamine

Chemical Property:

Boiling Point:296.8±40.0 °C(Predicted)
PKA:9.65±0.40(Predicted)
PSA：55.28000
Density:1.104±0.06 g/cm3(Predicted)
LogP:1.49530
XLogP3:-0.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:191.142247555
Heavy Atom Count:14
Complexity:167

Purity/Quality:

98% ^*data from raw suppliers

(R,R)-N-Benzyl-3,4-trans-diaminopyrrolidine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(C(CN1CC2=CC=CC=C2)N)N
Isomeric SMILES:C1[C@H]([C@@H](CN1CC2=CC=CC=C2)N)N

Technology Process of (3R,4R)-1-benzylpyrrolidine-3,4-diamine

There total 9 articles about (3R,4R)-1-benzylpyrrolidine-3,4-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 140134-20-9
(3R,4R)-3,4-diazido-1-benzylpyrrolidine

: 140134-21-0,246149-02-0
(3S,4S)-1-benzyl-pyrrolidine-3,4-diamine

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol;
DOI:10.1080/00397910802139304

Reference yield:

: 104351-40-8,1227269-36-4
(3S,4S)-1-benzyl-3,4-pyrrolidinediyl bis(methanesulfonate)

: 140134-21-0,246149-02-0
(3S,4S)-1-benzyl-pyrrolidine-3,4-diamine

Guidance literature:: Multi-step reaction with 2 steps

1: 52 percent / NaN₃ / dimethylformamide / 100 °C

2: 99 percent / hydrogen / Pd/C / ethanol / 20 °C

With sodium azide; hydrogen; palladium on activated charcoal; In ethanol; N,N-dimethyl-formamide;
DOI:10.1016/j.tetlet.2006.09.147

Reference yield:

: 90365-74-5,330152-66-4
(3S,4S)-(+)-1-benzyl-3,4-pyrrolidinediol

: 140134-21-0,246149-02-0
(3S,4S)-1-benzyl-pyrrolidine-3,4-diamine

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / HN₃; DEAD; PPh₃

2: LiAlH₄ / tetrahydrofuran / 0.5 h / Heating

With lithium aluminium tetrahydride; tris-(2-chloro-ethyl)-amine; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; 1: Substitution / 2: Reduction;
DOI:10.1021/jo991628z