4-((4-Chlorophenyl)hydroxymethyl)-3-methyl-1-oxaspiro(4.5)dec-3-en-2-one

Base Information

Chemical Name:4-((4-Chlorophenyl)hydroxymethyl)-3-methyl-1-oxaspiro(4.5)dec-3-en-2-one
CAS No.:86560-17-0
Molecular Formula:C₁₇H₁₉ClO₃
Molecular Weight:306.789
Hs Code.:
DSSTox Substance ID:DTXSID601006922
Mol file:86560-17-0.mol

Synonyms:BRN 5090068;86560-17-0;4-((4-Chlorophenyl)hydroxymethyl)-3-methyl-1-oxaspiro(4.5)dec-3-en-2-one;1-Oxaspiro(4.5)dec-3-en-2-one, 4-((4-chlorophenyl)hydroxymethyl)-3-methyl-;4-Chlorohydroxybenzyl-3 methyl-2 cyclohexane spiro-4,4-butene-2 olide-4 [French];4-Chlorohydroxybenzyl-3 methyl-2 cyclohexane spiro-4,4-butene-2 olide-4;C17H19ClO3;C17-H19-Cl-O3;DTXSID601006922;1-Oxaspiro[4.5]dec-3-en-2-one,4-[(4-chlorophenyl)hydroxymethyl]-3-methyl-;LS-99598;4-[(4-CHLOROPHENYL)(HYDROXY)METHYL]-3-METHYL-1-OXASPIRO[4.5]DEC-3-EN-2-ONE

Suppliers and Price of 4-((4-Chlorophenyl)hydroxymethyl)-3-methyl-1-oxaspiro(4.5)dec-3-en-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-OXASPIRO(4.5)DEC-3-EN-2-ONE, 4-((4-CHLOROPHENYL)HYDROXYMETHYL)-3-MET HYL- 95.00%
5MG
$ 498.12

Total 2 raw suppliers

Chemical Property of 4-((4-Chlorophenyl)hydroxymethyl)-3-methyl-1-oxaspiro(4.5)dec-3-en-2-one

Chemical Property:

Vapor Pressure:1.09E-11mmHg at 25°C
Boiling Point:521.2°C at 760 mmHg
Flash Point:269°C
PSA：46.53000
Density:1.28g/cm³
LogP:3.94960
XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:306.1022722
Heavy Atom Count:21
Complexity:443

Purity/Quality:: 1-OXASPIRO(4.5)DEC-3-EN-2-ONE, 4-((4-CHLOROPHENYL)HYDROXYMETHYL)-3-MET HYL- 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C2(CCCCC2)OC1=O)C(C3=CC=C(C=C3)Cl)O

Technology Process of 4-((4-Chlorophenyl)hydroxymethyl)-3-methyl-1-oxaspiro(4.5)dec-3-en-2-one

There total 3 articles about 4-((4-Chlorophenyl)hydroxymethyl)-3-methyl-1-oxaspiro(4.5)dec-3-en-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 86560-08-9
4-(4-Chloro-benzoyl)-3-methyl-1-oxa-spiro[4.5]dec-3-en-2-one

: 86560-17-0
4-[(4-Chloro-phenyl)-hydroxy-methyl]-3-methyl-1-oxa-spiro[4.5]dec-3-en-2-one

Guidance literature:: With sodium tetrahydroborate; In methanol; Yield given;

Reference yield:

: 58887-89-1
3-methyl-2-oxo-1-oxa-spiro[4.5]dec-3-ene-4-carbonyl chloride

: 86560-17-0
4-[(4-Chloro-phenyl)-hydroxy-methyl]-3-methyl-1-oxa-spiro[4.5]dec-3-en-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 66 percent / AlCl₃ / 1,2-dichloro-ethane / Ambient temperature

2: NaBH₄ / methanol

With sodium tetrahydroborate; aluminium trichloride; In methanol; 1,2-dichloro-ethane;

Reference yield:

: 108-90-7
chlorobenzene

: 86560-17-0
4-[(4-Chloro-phenyl)-hydroxy-methyl]-3-methyl-1-oxa-spiro[4.5]dec-3-en-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 66 percent / AlCl₃ / 1,2-dichloro-ethane / Ambient temperature

2: NaBH₄ / methanol

With sodium tetrahydroborate; aluminium trichloride; In methanol; 1,2-dichloro-ethane;