4-(3-(bis(3,5-difluorophenyl)(hydroxy)methyl)-1H-1,2,4-triazol-1-yl)-2,6-dichlorophenol

Base Information

Chemical Name:4-(3-(bis(3,5-difluorophenyl)(hydroxy)methyl)-1H-1,2,4-triazol-1-yl)-2,6-dichlorophenol
CAS No.:1202206-81-2
Molecular Formula:C₂₁H₁₁Cl₂F₄N₃O₂
Molecular Weight:484.237
Hs Code.:

Synonyms:4-(3-(bis(3,5-difluorophenyl)(hydroxy)methyl)-1H-1,2,4-triazol-1-yl)-2,6-dichlorophenol

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Chemical Property of 4-(3-(bis(3,5-difluorophenyl)(hydroxy)methyl)-1H-1,2,4-triazol-1-yl)-2,6-dichlorophenol

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Technology Process of 4-(3-(bis(3,5-difluorophenyl)(hydroxy)methyl)-1H-1,2,4-triazol-1-yl)-2,6-dichlorophenol

There total 2 articles about 4-(3-(bis(3,5-difluorophenyl)(hydroxy)methyl)-1H-1,2,4-triazol-1-yl)-2,6-dichlorophenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

: 1202207-11-1
ethyl 1-(3,5-dichloro-4-(4-methoxybenzyloxy)phenyl)-1H-1,2,4-triazole-3-carboxylate

: 62351-47-7
3,5-difluorophenylmagnesium bromide

: 1202206-81-2
4-(3-(bis(3,5-difluorophenyl)(hydroxy)methyl)-1H-1,2,4-triazol-1-yl)-2,6-dichlorophenol

Guidance literature:: ethyl 1-(3,5-dichloro-4-(4-methoxybenzyloxy)phenyl)-1H-1,2,4-triazole-3-carboxylate; 3,5-difluorophenylmagnesium bromide; In tetrahydrofuran;

With water; ammonium chloride; In ethyl acetate;

With trifluoroacetic acid; In dichloromethane; for 1h;