62351-47-7

Basic information

• Product Name: 3,5-DIFLUOROPHENYLMAGNESIUM BROMIDE
• Synonyms: 3,5-DIFLUOROPHENYLMAGNESIUM BROMIDE;3,5-DIFLUOROPHENYLMAGNESIUM BROMIDE, 0.5M SOLUTION IN TETRAHYDROFURAN;3,5-difluorophenylmagnesium bromide solution;3,5-Difluorophenylmagnesium bromide,0.5M solution in THF;3,5-Difluorophenylmagnesium bromide solution 0.5 in THF;3,5-Difluorophenylmagnesium bromide, 0.5M solution in THF, AcroSeal;3,5-DifluorophenylMagnesiuM broMide, 0.50M in 2-MeTHF;MagnesiuM broMide 3,5-difluorobenzenide
• CAS NO: 62351-47-7
• Molecular Formula: C₆H₃BrF₂Mg
• Molecular Weight: 217.29
• Product Categories: Aryl;Grignard Reagents;Organometallic Reagents;Chemical Synthesis;Grignard Reagents;Organometallic Reagents;Grignard Reagent
• Mol File: 62351-47-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 65 °C
• Flash Point: <1 °F
• Appearance: /
• Density: 0.971 g/mL at 25 °C
• Vapor Pressure: 82.7mmHg at 25°C
• Storage Temp.: 2-8°C
• Sensitive: Air & Moisture Sensitive
• CAS DataBase Reference: 3,5-DIFLUOROPHENYLMAGNESIUM BROMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-DIFLUOROPHENYLMAGNESIUM BROMIDE(62351-47-7)
• EPA Substance Registry System: 3,5-DIFLUOROPHENYLMAGNESIUM BROMIDE(62351-47-7)

Safety Data

• Hazard Codes: F,C,Xn
• Statements: 11-14-19-22-34-36/37-40
• Safety Statements: 16-26-33-36/37/39-45-36/37
• RIDADR: UN 2924 3/PG 2
• WGK Germany: 1
• HazardClass: 3
• Hazardous Substances Data: 62351-47-7(Hazardous Substances Data)

Usage

Chemical Properties

Tan liquid

Uses

3,5-Difluorophenylmagnesium bromide can be used:As a starting material in the synthesis of cis-2-phenyl-1-amino-cyclopentanes as AMPA receptor potentiators.To prepare copper(I) complexes, which are used as luminescent guest molecules in organic light-emitting diodes (OLEDs).As an intermediate in the synthesis of 2-aminoethylbenzofuran H3 receptor antagonists.

InChI:InChI=1/C6H3F2.BrH.Mg/c7-5-2-1-3-6(8)4-5;;/h2-4H;1H;/q-1;;+2/p-1

Upstream product

• 461-96-1 3,5-difluorobromobenzene 

Downstream Products

• 79538-22-0 1-allyl-3,5-difluorobenzene 
• 654062-92-7 1-(3,5-difluorophenyl)-3-hydroxy-3-(3-hydroxyphenyl)propyl-4-[4-(methylsulfonyl)benzyl]homopiperazine 
• 957121-16-3 methyl 5-(3,5-difluorophenyl)-2,2-dimethyl-5-oxopentanoate 
• 957121-37-8 N-[(SS,1R)-2-{[tert-butyl(dimethyl)silyl]oxy}-1-(3,5-difluorophenyl)ethyl]-2-methylpropane-2-sulfinamide 
• 957121-78-7 6-(3,5-difluorophenyl)-3,3-dimethylpiperidine-2,4-dione 
• 820971-68-4 tert-butyl 3-(3,5-difluorophenyl)azetidine-1-carboxylate 
• 59-31-4 2-quinolone 
• 1070872-75-1 (-)-(4R,5R)-5-(3,5-difluoro-benzoyl)-2,2-dimethyl-[1,3]dioxolane-4-carboxylic acid dimethylamide 
• 1146593-99-8 (3,5-difluorophenyl)cycloheptane 
• 138074-23-4 trans-4-pentyl-trans-4'-(3,5-difluorophenyl)-1,1'-bi(cyclohexyl) 
• 138074-23-4 trans-4-pentyl-cis-4'-(3,5-difluorophenyl)-1,1'-bi(cyclohexyl) 
• 1202206-81-2 4-(3-(bis(3,5-difluorophenyl)(hydroxy)methyl)-1H-1,2,4-triazol-1-yl)-2,6-dichlorophenol 
• 856413-70-2 (4S,5R)-1-[(3R)-3-(3,5-difluorophenyl)-3-(tetrahydro-2H-pyran-4-yl)propanoyl]-3,4-dimethyl-5-phenylimidazolidin-2-one 

Relevant articles and documents

Room-Temperature Palladium(II)-Catalyzed Direct 2-Arylation of Indoles with Tetraarylstannanes

A palladium(II)-catalyzed direct 2-arylation of indoles by tetraarylstannanes with oxygen (balloon) as the oxidant at room temperature has been developed. Various tetraarylstannanes can be employed as aryl sources for 2-arylation of indoles in up to 89% yield, providing a practical and efficient catalytic protocol for accessing 2-arylindoles.