5-(4-MorpholinylMethyl) δ-Tocopherol

Base Information

• Chemical Name: 5-(4-MorpholinylMethyl) δ-Tocopherol
• CAS No.: 936230-68-1
• Molecular Formula: C₃₂H₅₅NO₃
• Molecular Weight: 501.794
• Mol file: 936230-68-1.mol

Synonyms:(2R,4'R,8'R)-5-(morpholinomethyl)-δ-tocopherol

Chemical Property of 5-(4-MorpholinylMethyl) δ-Tocopherol

Chemical Property:

• Boiling Point: 584.6±50.0 °C(Predicted)
• PKA: 10.54±0.40(Predicted)
• Density: 0.988±0.06 g/cm3(Predicted)

Purity/Quality:

97% ^*data from raw suppliers

5-(4-Morpholinylmethyl)δ-Tocopherol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: β-Tocopherol intermediate.

Technology Process of 5-(4-MorpholinylMethyl) δ-Tocopherol

There total 1 articles about 5-(4-MorpholinylMethyl) δ-Tocopherol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

morpholine (110-91-8,99108-56-2) + formaldehyd (50-00-0,30525-89-4,61233-19-0) + delta tocopherol (119-13-1,78656-14-1) → (2R,4'R,8'R)-7-(morpholinomethyl)-δ-tocopherol + (2R,4'R,8'R)-5,7-bis(morpholinomethyl)-δ-tocopherol (182558-04-9) + (2R,4'R,8'R)-5-(morpholinomethyl)-δ-tocopherol (936230-68-1)

Guidance literature:

morpholine; formaldehyd; at 70 - 80 ℃; for 2.33333h;

delta tocopherol; at 20 - 80 ℃; for 1.75h; Further stages.;

DOI:10.1002/ejoc.200600874

Reference yield: 95.0%

(2R,4'R,8'R)-5-(morpholinomethyl)-δ-tocopherol (936230-68-1) → 5,8-dimethyltocol (16698-35-4)

Guidance literature:

With sodium hydroxide; sodium tetrahydroborate; In tert-butyl alcohol; for 10h; Heating;

DOI:10.1002/ejoc.200600874

upstream raw materials:

morpholine

formaldehyd

delta tocopherol

Downstream raw materials:

5,8-dimethyltocol