4'-{5-[(4R)-2,2,4-trimethyl-1,3-dioxolan-4-yl]thiazol-2-ylthio}acetophenone

Base Information

Chemical Name:4'-{5-[(4R)-2,2,4-trimethyl-1,3-dioxolan-4-yl]thiazol-2-ylthio}acetophenone
CAS No.:161387-24-2
Molecular Formula:C₁₇H₁₉NO₃S₂
Molecular Weight:349.475
Hs Code.:

Synonyms:4'-{5-[(4R)-2,2,4-trimethyl-1,3-dioxolan-4-yl]thiazol-2-ylthio}acetophenone

Suppliers and Price of 4'-{5-[(4R)-2,2,4-trimethyl-1,3-dioxolan-4-yl]thiazol-2-ylthio}acetophenone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4'-{5-[(4R)-2,2,4-trimethyl-1,3-dioxolan-4-yl]thiazol-2-ylthio}acetophenone

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4'-{5-[(4R)-2,2,4-trimethyl-1,3-dioxolan-4-yl]thiazol-2-ylthio}acetophenone

There total 4 articles about 4'-{5-[(4R)-2,2,4-trimethyl-1,3-dioxolan-4-yl]thiazol-2-ylthio}acetophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 161387-24-2
4'-{5-[(4R)-2,2,4-trimethyl-1,3-dioxolan-4-yl]thiazol-2-ylthio}acetophenone

Guidance literature:

Reference yield:

: 403-42-9
1-(4-fluorophenyl)ethanone

: 161387-23-1
2-mercapto-5-[(4R)-2,2,4-trimethyl-1,3-dioxolan-4-yl]thiazole

: 161387-24-2
4'-{5-[(4R)-2,2,4-trimethyl-1,3-dioxolan-4-yl]thiazol-2-ylthio}acetophenone

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 130 ℃; for 1.5h; Yield given;
DOI:10.1021/jm00020a008

Reference yield:

: 159615-85-7
(R)-5-(1,2-dihydroxyprop-2-yl)-2-(methylthio)thiazole

: 161387-24-2
4'-{5-[(4R)-2,2,4-trimethyl-1,3-dioxolan-4-yl]thiazol-2-ylthio}acetophenone

Guidance literature:: Multi-step reaction with 3 steps

1: PTSA / acetone / 0.75 h / Heating

2: NaSMe / dimethylformamide / 0.5 h / 130 °C

3: K₂CO₃ / dimethylformamide / 1.5 h / 130 °C

With potassium carbonate; toluene-4-sulfonic acid; sodium thiomethoxide; In N,N-dimethyl-formamide; acetone;
DOI:10.1021/jm00020a008